THE PPM1D ENCODED PHOSPHATASE WIP1 IS A NOVEL ONCOGENE AND POTENTIAL THERAPEUTIC TARGET IN NEUROBLASTOMA AND MEDULLOBLASTOMA

被引:0
|
作者
Milosevic, J. [1 ]
Treis, D. [1 ]
Malin, M. [1 ]
Fransson, S. [2 ]
Sveinbjornsson, B. [3 ]
Eissler, N. [1 ]
Baryawno, N. [1 ]
Tanino, K. [4 ]
Selivanova, G. [5 ]
Sakaguchi, K. [4 ]
Martinsson, T. [2 ]
Johnsen, J. I. [1 ]
Kogner, P. [1 ]
机构
[1] Karolinska Inst, Womens & Childrens Hlth, Stockholm, Sweden
[2] Gothenburg Univ, Dept Clin Genet, Inst Biomed, Gothenburg, Sweden
[3] Univ Tromso, Div Immunol IMB, Tromso, Norway
[4] Hokkaido Univ, Fac Sci, Biol Chem Lab, Dept Chem, Sapporo, Hokkaido 060, Japan
[5] Karolinska Inst, Dept Microbiol Tumor & Cell Biol, Stockholm, Sweden
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P-382
引用
收藏
页码:S332 / S332
页数:1
相关论文
共 50 条
  • [21] PPM1D/Wip1 is amplified, overexpressed, and mutated in human non-Hodgkin's lymphomas
    Pilevneli, Hatice
    Doeger, Firuzan
    Karagenc, Levent
    Kozaci, Didem
    Eren, Mehtap Kilic
    MOLECULAR BIOLOGY REPORTS, 2024, 51 (01)
  • [22] The potential oncogenic significance of Wip1 in neuroblastoma
    Milosevic, Jelena
    Wickstrom, Malin
    Elfman, Lotta
    Baryawno, Ninib
    Sveinbjornsson, Baldur
    Martinsson, Tommy
    Johnsen, John Inge
    Kogner, Per
    CANCER RESEARCH, 2013, 73 (08)
  • [23] The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants
    Buss, M. C.
    Remke, M.
    Lee, J.
    Gandhi, K.
    Schniederjan, M. J.
    Kool, M.
    Northcott, P. A.
    Pfister, S. M.
    Taylor, M. D.
    Castellino, R. C.
    ONCOGENE, 2015, 34 (09) : 1126 - 1140
  • [24] The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants
    M C Buss
    M Remke
    J Lee
    K Gandhi
    M J Schniederjan
    M Kool
    P A Northcott
    S M Pfister
    M D Taylor
    R C Castellino
    Oncogene, 2015, 34 : 1126 - 1140
  • [25] PPM1D/WIP1 phosphatase mediates basal and genotoxic stress-induced autophagy via ULK-1 de-phosphorylation
    Ak, C.
    Karlitepe, A.
    Pilevneli, H.
    Kaygusuz, N.
    Eren, M. K. Kilic
    ANNALS OF ONCOLOGY, 2023, 34 : S213 - S213
  • [26] PPM1D Is a Therapeutic Target in Childhood Neural Tumors
    Milosevic, Jelena
    Treis, Diana
    Fransson, Susanne
    Gallo-Oller, Gabriel
    Sveinbjoernsson, Baldur
    Eissler, Nina
    Tanino, Keiji
    Sakaguchi, Kazuyasu
    Martinsson, Tommy
    Wickstroem, Malin
    Kogner, Per
    Johnsen, John Inge
    CANCERS, 2021, 13 (23)
  • [27] The wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases
    Yamaguchi, Hiroshi
    Durell, Stewart R.
    Chatterjee, Deb K.
    Anderson, Carl W.
    Appella, Ettore
    BIOCHEMISTRY, 2007, 46 (44) : 12594 - 12603
  • [28] WIP1 phosphatase as pharmacological target in cancer therapy
    Pechackova, Sona
    Burdova, Kamila
    Macurek, Libor
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2017, 95 (06): : 589 - 599
  • [29] Wip1 phosphatase: a new target for anticancer therapy?
    Maprayil, Sophia
    EXPERT REVIEW OF ANTICANCER THERAPY, 2013, 13 (12) : 1354 - 1354
  • [30] WIP1 phosphatase as pharmacological target in cancer therapy
    Soňa Pecháčková
    Kamila Burdová
    Libor Macurek
    Journal of Molecular Medicine, 2017, 95 : 589 - 599