Systemic Abscopal Effect of Low-dose Radiotherapy (2 Gy x2) against Palatine Tonsil Follicular Lymphoma

被引：2
|
作者：
Togitani, Kazuto [1 ]
Asagiri, Tadashi
Iguchi, Mitsuko
Igawa, Takuro
Yoshino, Tadashi
Kojima, Kensuke
机构：
[1] Kochi Univ, Kochi Med Sch, Dept Hematol, Kochi, Japan
来源：
INTERNAL MEDICINE | 2022年 / 61卷 / 20期
关键词：
Key words; low-dose radiotherapy; abscopal effect; CD5; follicular lymphoma; MARGINAL ZONE; EXPRESSION; RADIATION; PHASE-3; MUM1;
D O I：
10.2169/internalmedicine.8968-21
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 52-year-old man presented with palatine tonsillar swelling caused by follicular lymphoma. His tumor burden was low, but exacerbation of snoring and dysphagia was observed. Considering the first wave of coronavirus disease 2019 (COVID-19) pandemic, he received palliative 4-Gy irradiation to the tonsils in 2 fractions, which induced partial regression of tonsillar swellings and eradication of the circulating lymphoma cells. We suggest that low-dose radiotherapy triggered an abscopal effect of lymphoma, which allowed the patient time to receive COVID-19 vaccination before starting immunosuppressive chemo-immunotherapy.
引用
收藏
页码：3107 / 3110
页数：4
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