Systemic Abscopal Effect of Low-dose Radiotherapy (2 Gy x2) against Palatine Tonsil Follicular Lymphoma

被引：2
|
作者：
Togitani, Kazuto [1 ]
Asagiri, Tadashi
Iguchi, Mitsuko
Igawa, Takuro
Yoshino, Tadashi
Kojima, Kensuke
机构：
[1] Kochi Univ, Kochi Med Sch, Dept Hematol, Kochi, Japan
来源：
INTERNAL MEDICINE | 2022年 / 61卷 / 20期
关键词：
Key words; low-dose radiotherapy; abscopal effect; CD5; follicular lymphoma; MARGINAL ZONE; EXPRESSION; RADIATION; PHASE-3; MUM1;
D O I：
10.2169/internalmedicine.8968-21
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 52-year-old man presented with palatine tonsillar swelling caused by follicular lymphoma. His tumor burden was low, but exacerbation of snoring and dysphagia was observed. Considering the first wave of coronavirus disease 2019 (COVID-19) pandemic, he received palliative 4-Gy irradiation to the tonsils in 2 fractions, which induced partial regression of tonsillar swellings and eradication of the circulating lymphoma cells. We suggest that low-dose radiotherapy triggered an abscopal effect of lymphoma, which allowed the patient time to receive COVID-19 vaccination before starting immunosuppressive chemo-immunotherapy.
引用
收藏
页码：3107 / 3110
页数：4
相关论文
共 50 条
  • [1] Low-dose (2x2 Gy) Radiotherapy in Indolent Lymphoma
    Schick, U.
    Rossier, C.
    Weber, D. C.
    Ketterer, N.
    Miralbell, R.
    Mirimanoff, R. O.
    Ozsahin, M.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 75 (03): : S479 - S479
  • [2] Low-Dose Radiation Therapy (2 Gy x 2) in the Treatment of Orbital Lymphoma
    Fasola, Carolina E.
    Jones, Jennifer C.
    Huang, Derek D.
    Quynh-Thu Le
    Hoppe, Richard T.
    Donaldson, Sarah S.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2013, 86 (05): : 930 - 935
  • [3] Can Low Dose Radiation Therapy (2 x 2 Gy) be Used in Primary Bilateral Conjunctival Follicular Lymphoma?
    Cotting-Bodmer, S.
    Moulin, A.
    Herbort, C. P., Jr.
    Ketterer, N.
    Betz, M.
    Pica, A.
    Schalenbourg, A.
    KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, 2016, 233 (04) : 524 - 526
  • [4] LOW DOSE (2x2 Gy) RT IN INDOLENT LYMPHOMA
    Rossier, C.
    Schick, U.
    Weber, D.
    Miralbell, R.
    Mirimanoff, R. O.
    Ozsahin, M.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2009, 185 (09) : 634 - 634
  • [5] Low-Dose Radiation Therapy (2 Gy x 2) in the Treatment of Non-Hodgkin Lymphoma of the Ocular Adnexa
    Fasola, C.
    Jones, J. C.
    Huang, D.
    Le, Q.
    Hoppe, R. T.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2013, 87 (02): : S59 - S60
  • [6] Optimizing Low Dose Radiotherapy for Indolent Lymphomas: Comparing 4 Gy x 2 vs. 2 Gy x 2
    Burlile, J. F.
    Harmsen, W. S.
    Saifi, O.
    Laughlin, B.
    Kosydar, S.
    Sharifzadeh, Y.
    Frechette, K. M.
    Habermann, T. M.
    Bisneto, J. Villasboas
    Wang, Y.
    Hampe, P.
    Paludo, J.
    Hoppe, B. S.
    Rule, W. G.
    Peterson, J. L.
    Witzig, T.
    Micallef, I. N.
    Breen, W.
    Lester, S. C.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2024, 120 (02): : S176 - S177
  • [7] THE ROLE OF LOW-DOSE RADIOTHERAPY, 4GY IN 2 FRACTIONS, IN THE TREATMENT OF FOLICULAR LYMPHOMA: THE EXPERIENCE OF A SINGLE CENTER
    Ribeiro, T.
    Ramos, T.
    Pereira, I
    Freitas, J.
    Marques, A.
    Tavares, M.
    Pereira, D.
    Chacim, S.
    Domingues, N.
    Espirito Santo, A.
    Oliveira, I
    Martina, A.
    Moreira, I
    Viterbo, L.
    Castro, C.
    Henrique, R.
    Oliveira, A.
    Mariz, M.
    HAEMATOLOGICA, 2019, 104 : 184 - 184
  • [8] Response Rates and Recurrence Pattern Analysis after low-dose Radiotherapy with 2x2 Gy in indolent NHL
    Konig, L.
    Horner-Rieber, J.
    Gardyan, A.
    Debus, J.
    Herfarth, K.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2017, 193 : S5 - S6
  • [9] Efficacy of low-dose radiotherapy (2 Gy x 2) in the treatment of marginal zone and mucosa-associated lymphoid tissue lymphomas
    Cerrato, Marzia
    Orlandi, Erika
    Vella, Angelisa
    Bartoncini, Sara
    Iorio, Giuseppe C.
    Bongiovanni, Diego
    Capriotti, Francesco
    Boccomini, Carola
    Vassallo, Francesco
    Cavallin, Chiara
    De Luca, Viola
    Giglioli, Francesca R.
    Ricardi, Umberto
    Levis, Mario
    BRITISH JOURNAL OF RADIOLOGY, 2021, 94 (1123):
  • [10] Dose-Escalated, Intratumoral TLR9 Agonist and Low-Dose Radiation Induce Abscopal Effects in Follicular Lymphoma
    Kohrt, Holbrook E.
    Chu, Jaqueline
    Brody, Joshua
    Czerwinski, Debra K.
    Chester, Cariad
    Sadaram, Mohith
    Advani, Ranjana
    Kim, Youn H.
    Hoppe, Richard T.
    Knox, Susan J.
    Wapnir, Irene
    Tibshirani, Robert J.
    Levy, Ron
    BLOOD, 2014, 124 (21)
12345