Chiral phosphine-catalyzed enantioselective construction of γ-butenolides through substitution of Morita-Baylis-Hillman acetates with 2-trimethylsilyloxy furan

被引：284

作者：

Jiang, Ying-Qing ^{[1
]}

Shi, Yong-Ling ^{[1
]}

Shi, Min ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 23期

关键词：

D O I：

10.1021/ja802422d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral multifunctional phosphine (R)-N-(2'-diphenylphosphanyl-[1,1']binaphthalenyl-2-yl) methanesulfonamide L2 or (R)-N-(2'-diphenylphosphanyl-[1,1']binaphthalenyl-2-yl) acetamide L3 is an efficient catalyst in the substitutions of MBH acetates 1 with 2-trimethylsilyloxy furan 2 to provide y-butenolides 3 in good to excellent yields and enantiomeric excesses in the presence of water.

引用

页码：7202 / +

页数：3

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