Effect of diethylsulfoxide on the thermal denaturation of DNA

被引：44

作者：

Markarian, SA ^{[1
]}

Asatryan, AM ^{[1
]}

Grigoryan, KR ^{[1
]}

Sargsyan, HR ^{[1
]}

机构：

[1] Yerevan State Univ, Dept Chem, Yerevan 375049, Armenia

来源：

BIOPOLYMERS | 2006年 / 82卷 / 01期

关键词：

DNA; diethylsulfoxide; denaturation; ultraviolet-visible spectroscopy; densimetry;

D O I：

10.1002/bip.20454

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

DNA thermal denaturation has been investigated in aqueous solutions of diethylsulfoxide (DESO) by means of UV-vis and densimetry, methods. It is suggested that, on the one hand, the structural change of entire solutions and, on the other hand, a direct interaction of DESO with DNA are responsible for the observed peculiar behavior. The results obtained were compared with those of dimethylsulfoxide (DMSO), also known from literature (c) 2006 Wiley Periodicals, Inc.

引用

页码：1 / 5

页数：5

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