Dielectrophoretically Aligned Carbon Nanotubes to Control Electrical and Mechanical Properties of Hydrogels to Fabricate Contractile Muscle Myofibers

被引：233

作者：

Ramon-Azcon, Javier ^{[7
]}

Ahadian, Samad ^{[7
]}

Estili, Mehdi ^{[8
]}

Liang, Xiaobin ^{[7
]}

Ostrovidov, Serge ^{[7
]}

Kaji, Hirokazu ^{[9
]}

Shiku, Hitoshi ^{[6
]}

Ramalingam, Murugan ^{[7
,10
,11
]}

Nakajima, Ken ^{[7
]}

Sakka, Yoshio ^{[8
]}

Khademhosseini, Ali ^{[1
,2
,3
,4
,5
,7
]}

Matsue, Tomokazu ^{[6
,7
]}

机构：

[1] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Med,Ctr Biomed Engn, Cambridge, MA 02139 USA

[2] MIT, Harvard MIT Div Hlth Sci & Technol, Cambridge, MA 02139 USA

[3] Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02115 USA

[4] Kyung Hee Univ, Sch Dent, Dept Maxillofacial Biomed Engn, Seoul 130701, South Korea

[5] Kyung Hee Univ, Sch Dent, Inst Oral Biol, Seoul 130701, South Korea

[6] Tohoku Univ, Grad Sch Environm Studies, Sendai, Miyagi 9808579, Japan

[7] Tohoku Univ, WPI Adv Inst Mat Res, Sendai, Miyagi 9808577, Japan

[8] Natl Inst Mat Sci, Mat Proc Unit, Tsukuba, Ibaraki 3050047, Japan

[9] Tohoku Univ, Grad Sch Engn, Dept Bioengn & Robot, Sendai, Miyagi 9808579, Japan

[10] Ctr Stem Cell Res, Vellore 632002, Tamil Nadu, India

[11] Univ Strasbourg, INSERM, U977, Fac Chirurg Dent, F-67085 Strasbourg, France

来源：

ADVANCED MATERIALS | 2013年 / 25卷 / 29期

关键词：

carbon nanotubes; dielectrophoresis; gelatin methacrylate hydrogel; electrical conductivity; muscle cell differentiation; GELATIN METHACRYLATE; NANOFIBERS; MEMBRANES; BIOLOGY;

D O I：

10.1002/adma.201301300

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Dielectrophoresis is used to align carbon nanotubes (CNTs) within gelatin methacrylate (GelMA) hydrogels in a facile and rapid manner. Aligned GelMA-CNT hydrogels show higher electrical properties compared with pristine and randomly distributed CNTs in GelMA hydrogels. The muscle cells cultured on these materials demonstrate higher maturation compared with cells cultured on pristine and randomly distributed CNTs in GelMA hydrogels. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4028 / 4034

页数：7

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