Drug-induced lupus and autoimmune hepatitis secondary to infliximab for psoriasis

被引：28

作者：

Dang, Lucy J. ^{[1
,3
]}

Lubel, John S. ^{[2
,3
]}

Gunatheesan, Shyamalar ^{[1
]}

Hosking, Patrick ^{[4
]}

Su, John ^{[1
,3
,5
]}

机构：

[1] Monash Univ, Dept Dermatol, Melbourne, Vic 3004, Australia

[2] Monash Univ, Box Hill Hosp, Melbourne, Vic 3004, Australia

[3] Monash Univ, Eastern Hlth Clin Sch, Melbourne, Vic 3004, Australia

[4] Univ Melbourne, Melbourne, Vic, Australia

[5] Univ Melbourne, Dept Paediat, Melbourne, Vic, Australia

来源：

AUSTRALASIAN JOURNAL OF DERMATOLOGY | 2014年 / 55卷 / 01期

关键词：

adverse drug reaction; dermatology; gastroenterology; hepatitis; psoriasis; THERAPY; AUTOANTIBODIES; ARTHRITIS;

D O I：

10.1111/ajd.12054

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We describe a case of previously unreported autoimmune hepatitis and lupus-like syndrome induced by infliximab treatment for chronic plaque psoriasis. The condition resolved after withdrawal of infliximab, with the liver injury having been reversed and minimal periportal fibrosis. In a two-part discussion we review the current literature on the pharmacology of infliximab and provide recommendations for management of infliximab side effects.

引用

页码：75 / 79

页数：5

共 20 条

[1] Effects of short-term infliximab therapy on autoantibodies in systemic lupus erythematosus [J].

Aringer, Martin ;

Steiner, Guenter ;

Graninger, Winfried B. ;

Hoefler, Elisabeth ;

Steiner, Carl W. ;

Smolen, Josef S. .

ARTHRITIS AND RHEUMATISM, 2007, 56 (01) :274-279

[2] Infliximab for patients with plaque psoriasis and severe psychiatric comorbidity [J].

Bassukas, I. D. ;

Hyphantis, T. ;

Gamvroulia, C. ;

Gaitanis, G. ;

Mavreas, V. .

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2008, 22 (02) :257-258

[3]

Centocor, 2004, IMP DRUG WARN

[4] Autoimmune hepatitis associated with infliximab in a patient with palmoplantar pustular psoriaisis [J].

Fairhurst, D. A. ;

Sheehan-Dare, R. .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2009, 34 (03) :422-422

[5] Infliximab therapy in rheumatoid arthritis and ankylosing spondylitis-induced specific antinuclear and antiphospholipid autoantibodies without autoimmune clinical manifestations: a two-year prospective study [J].

Ferraro-Peyret, C ;

Coury, F ;

Tebib, JG ;

Bienvenu, J ;

Fabien, N .

ARTHRITIS RESEARCH & THERAPY, 2004, 6 (06) :R535-R543

[6]

Goujon Catherine, 2010, J Am Acad Dermatol, V63, pe43, DOI 10.1016/j.jaad.2009.02.029

[7] Simplified criteria for the diagnosis of autoimmune hepatitis [J].

Hennes, Elke M. ;

Zeniya, Mikio ;

Czaja, Albert. J. ;

Pares, Albert ;

Dalekos, George N. ;

Krawitt, Edward L. ;

Bittencourt, Paulo L. ;

Porta, Gilda ;

Boberg, Kirsten M. ;

Hofer, Harald ;

Bianchi, Francesco B. ;

Shibata, Minoru ;

Schramm, Christoph ;

de Torres, Barbara Eisenmann ;

Galle, Peter R. ;

McFarlane, Ian ;

Dienes, Hans-Peter ;

Lohse, Ansgar W. .

HEPATOLOGY, 2008, 48 (01) :169-176

[8] Autoantibodies in psoriasis as predictors for loss of response and anti-infliximab antibody induction [J].

Hoffmann, J. H. O. ;

Hartmann, M. ;

Enk, A. H. ;

Hadaschik, E. N. .

BRITISH JOURNAL OF DERMATOLOGY, 2011, 165 (06) :1355-1358

[9] Opportunistic autoimmune disorders From immunotherapy to immune dysregulation [J].

Kong, Yi-chi M. ;

Wei, Wei-Zen ;

Tomer, Yaron .

YEAR IN IMMUNOLOGY 2, 2010, 1183 :222-236

[10] Review and expert opinion on prevention and treatment of infliximab-related infusion reactions [J].

Lecluse, L. L. A. ;

Piskin, G. ;

Mekkes, J. R. ;

Bos, J. D. ;

de Rie, M. A. .

BRITISH JOURNAL OF DERMATOLOGY, 2008, 159 (03) :527-536

← 1 2 →