Differential Effects of Startle on Reaction Time for Finger and Arm Movements

Carlsen AN, Chua R, Inglis JT, Sanderson DJ, Franks IM. Differential effects of startle on reaction time for finger and arm movements. J Neurophysiol 101: 306-314, 2009. First published November 12, 2008; doi:10.1152/jn.00878.2007. Recent studies using a reaction time (RT) task have reported that a preprogrammed response could be triggered directly by a startling acoustic stimulus (115-124 dB) presented along with the usual "go" signal. It has been suggested that details of the upcoming response could be stored subcortically and are accessible by the startle volley, directly eliciting the correct movement. However, certain muscles (e. g., intrinsic hand) are heavily dependent on cortico-motoneuronal connections and thus would not be directly subject to the subcortical startle volley in a similar way to muscles whose innervations include extensive reticular connections. In this study, 14 participants performed 75 trials in each of two tasks within a RT paradigm: an arm extension task and an index finger abduction task. In 12 trials within each task, the regular go stimulus (82 dB) was replaced with a 115-dB startling stimulus. Results showed that, in the arm task, the presence of a startle reaction led to significantly shorter latency arm movements compared with the effect of the increased stimulus intensity alone. In contrast, for the finger task, no additional decrease in RT caused by startle was observed. Taken together, these results suggest that only movements that involve muscles more strongly innervated by subcortical pathways are susceptible to response advancement by startle.