The fuzzification of platelet aggregation response for interpretation of interactive effect of combination aspirin-ticlopidine therapy in patients with stroke

被引：1
|
作者：
Helgason, CM [1 ]
Jobe, TH [1 ]
Brace, LD [1 ]
Mordeson, J [1 ]
机构：
[1] Univ Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USA
来源：
18TH INTERNATIONAL CONFERENCE OF THE NORTH AMERICAN FUZZY INFORMATION PROCESSING SOCIETY - NAFIPS | 1999年
关键词：
D O I：
10.1109/NAFIPS.1999.781699
中图分类号：
TP18 [人工智能理论];
学科分类号：
081104 ; 0812 ; 0835 ; 1405 ;
摘要：
Current therapy for prevention of heart attack and stroke includes the use of aspirin and other antiplatelet agents. These latter are used in an all or none fashion, one dosage for all. Recent studies suggest that different persons respond to different dosage of an antiplatelet agent to certain degree and that this response has clinical importance in relation to their intended preventive purpose. This study uses fuzzy theory to describe and study individual response to the antiplatlet medications aspirin and ticlopidine, alone and in combination.
引用
收藏
页码：283 / 287
页数：5
相关论文
共 50 条
  • [31] EFFECT OF THERAPY ON PLATELET ACTIVATING FACTOR-INDUCED AGGREGATION IN ACUTE STROKE
    JOSEPH, R
    WELCH, KMA
    DANDREA, G
    STROKE, 1989, 20 (05) : 609 - 611
  • [32] Effect of naftidrofuryl on platelet aggregation in plasma from aspirin treated patients:: an in vitro study
    Le Dévéhat, C
    Khodabandehlou, T
    Mosnier, M
    CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 2000, 22 (03) : 197 - 204
  • [33] EFFECT OF PICOTAMIDE AND ASPIRIN, COMBINED OR ALONE, ON PLATELET-AGGREGATION IN PATIENTS WITH CEREBRAL INFARCTION
    DANDREA, G
    PERINI, F
    HASSELMARK, L
    ALECCI, M
    CANANZI, AR
    FUNCTIONAL NEUROLOGY, 1995, 10 (02) : 91 - 98
  • [34] Effect of different aspirin doses on platelet aggregation in patients with stable coronary artery disease
    Malhotra, S
    Sharma, YP
    Grover, A
    Majumdar, S
    Hanif, SM
    Bhargava, VK
    Bhatnagar, A
    Pandhi, P
    INTERNAL MEDICINE JOURNAL, 2003, 33 (08) : 350 - 354
  • [35] EFFECT OF A SINGLE ORAL DOSE OF ASPIRIN ON THE PLATELET-AGGREGATION RESPONSE TO ARACHIDONIC-ACID
    BYE, A
    LEWIS, Y
    OGRADY, J
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 7 (03) : 283 - 286
  • [36] Effect of ticlopidine on exercise-induced platelet aggregation and exercise tolerance time in patients with ischemic heart disease
    Tsuruta, M
    Utsunomiya, T
    Yoshida, K
    Ogata, T
    Tsuji, S
    Tokushima, T
    Higuchi, H
    Matsuo, S
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1999, 33 (04) : 659 - 664
  • [37] Effect of nimodipine on cell calcium concentration and platelet aggregation in patients with ischemic stroke
    Pryanikova, NA
    Dukhanin, AS
    Stakhovskaya, LV
    Chekneva, NS
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1996, 121 (03) : 291 - 293
  • [38] Overcoming aspirin resistance: Increased platelet inhibition with combination aspirin and clopidogrel and high dose aspirin therapy in aspirin resistant patients with peripheral vascular disease
    Wong, Shen
    Morel-Kopp, Marie-Christine
    Chen, Qiang
    Appleberg, Michael
    Ward, Christopher M.
    Lewis, David R.
    THROMBOSIS AND HAEMOSTASIS, 2006, 95 (06) : 1042 - 1043
  • [39] Stroke and aspirin non-responder patients: Relation with hypertension and platelet response to adenosine diphosphate
    Godeneche, G.
    Sorel, N.
    Ragot, S.
    Chomel, J. C.
    Neau, J. P.
    Macchi, L.
    PLATELETS, 2009, 20 (07) : 471 - 477
  • [40] The Effect of Difference Time Taking Aspirin, Clopidogrel on Platelet Aggregation in Patients with Acute Coronary Syndrome
    Li, Z.
    Liu, F.
    Cui, W.
    Xie, R. Q.
    Yang, X. C.
    Ren, X. J.
    Liu, J.
    CARDIOLOGY, 2009, 114 : 111 - 111
12345