The fuzzification of platelet aggregation response for interpretation of interactive effect of combination aspirin-ticlopidine therapy in patients with stroke

被引:1
|
作者
Helgason, CM [1 ]
Jobe, TH [1 ]
Brace, LD [1 ]
Mordeson, J [1 ]
机构
[1] Univ Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USA
关键词
D O I
10.1109/NAFIPS.1999.781699
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Current therapy for prevention of heart attack and stroke includes the use of aspirin and other antiplatelet agents. These latter are used in an all or none fashion, one dosage for all. Recent studies suggest that different persons respond to different dosage of an antiplatelet agent to certain degree and that this response has clinical importance in relation to their intended preventive purpose. This study uses fuzzy theory to describe and study individual response to the antiplatlet medications aspirin and ticlopidine, alone and in combination.
引用
收藏
页码:283 / 287
页数:5
相关论文
共 50 条
  • [21] Effect of Vorapaxar Alone and in Combination with Aspirin on Bleeding Time and Platelet Aggregation in Healthy Adult Subjects
    Kraft, W. K.
    Gilmartin, J. H.
    Chappell, D. L.
    Gheyas, F.
    Walker, B. M.
    Nagalla, S.
    Naik, U. P.
    Horrow, J. C.
    Wrishko, R. E.
    Zhang, S.
    Anderson, M. S.
    CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2016, 9 (04): : 221 - 227
  • [22] Association of Recurrent Cerebral Infarction With Adenosine Diphosphate- and Collagen-Induced Platelet Aggregation in Patients Treated With Ticlopidine and/or Aspirin
    Abumiya, Takeo
    Houkin, Kiyohiro
    JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2011, 20 (04): : 319 - 323
  • [23] The measure of interaction of aspirin-clopidogrel for ex vivo platelet aggregation in patients with ischemic stroke
    Helgason, CM
    Mordeson, JN
    Cheng, SC
    Nutescu, E
    Jobe, TH
    Brace, LD
    ANNALS OF NEUROLOGY, 2000, 48 (03) : 424 - 424
  • [24] The effect of aspirin on blood platelet aggregation and thrombinogenesis in patients with myocardial infarction (MI)
    Kotschy, M
    Michalski, A
    Kotschy, D
    Swiatkowski, M
    THROMBOSIS AND HAEMOSTASIS, 1999, : 648 - 649
  • [25] Effect of high dose statin therapy on platelet function; statins reduce aspirin resistant platelet aggregation in patients with coronary heart disease
    Ebru Tirnaksiz
    Burak Pamukcu
    Huseyin Oflaz
    Yilmaz Nisanci
    Journal of Thrombosis and Thrombolysis, 2009, 27 : 24 - 28
  • [26] Effect of high dose statin therapy on platelet function; statins reduce aspirin resistant platelet aggregation in patients with coronary heart disease
    Tirnaksiz, Ebru
    Pamukcu, Burak
    Oflaz, Huseyin
    Nisanci, Yilmaz
    JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2009, 27 (01) : 24 - 28
  • [27] The effect of combination use of ticlopidine and aspirin on 30-day mortality in patients with acute myocardial infarction
    Mizuno, H
    Sato, H
    Kinjo, K
    Nakatani, D
    Shiotani, I
    Hishida, E
    Hirayama, A
    Kodama, K
    Hori, M
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (06) : 346A - 346A
  • [28] Abciximab, ticlopidine, and concomitant abciximab-ticlopidine therapy: Ex vivo platelet aggregation inhibition profiles in patients undergoing percutaneous coronary interventions
    Kleiman, NS
    Grazeiadei, N
    Maresh, K
    Taylor, RJ
    Frederick, B
    Lance, ET
    Effron, MB
    Jordan, RE
    Mascelli, MA
    AMERICAN HEART JOURNAL, 2000, 140 (03) : 492 - 501
  • [29] Response to aspirin therapy in patients with myeloproliferative neoplasms depends on the platelet count
    Gremmel, Thomas
    Gisslinger, Bettina
    Gisslinger, Heinz
    Panzer, Simon
    TRANSLATIONAL RESEARCH, 2018, 200 : 35 - 42
  • [30] Effect of aspirin and warfarin therapy in stroke patients with valvular strands
    Homma, S
    Di Tullio, MR
    Sciacca, RR
    Sacco, RL
    Mohr, JP
    STROKE, 2004, 35 (06) : 1436 - 1442