The fuzzification of platelet aggregation response for interpretation of interactive effect of combination aspirin-ticlopidine therapy in patients with stroke
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作者:
Helgason, CM
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Univ Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USAUniv Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USA
Helgason, CM
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Jobe, TH
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Univ Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USAUniv Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USA
Jobe, TH
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Brace, LD
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Univ Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USAUniv Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USA
Brace, LD
[1
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Mordeson, J
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Univ Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USAUniv Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USA
Mordeson, J
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机构:
[1] Univ Illinois, Coll Med, Dept Neurol, Chicago, IL 60612 USA
Current therapy for prevention of heart attack and stroke includes the use of aspirin and other antiplatelet agents. These latter are used in an all or none fashion, one dosage for all. Recent studies suggest that different persons respond to different dosage of an antiplatelet agent to certain degree and that this response has clinical importance in relation to their intended preventive purpose. This study uses fuzzy theory to describe and study individual response to the antiplatlet medications aspirin and ticlopidine, alone and in combination.