Nutritional management of Eosinophilic Gastroenteropathies: Case series from the community

被引:11
作者
Basilious, Alfred [1 ]
Liem, Joel [2 ]
机构
[1] Univ Windsor, Dept Biol, Windsor, ON N9B 3P4, Canada
[2] Windsor Allergy Asthma Educ Ctr, Schulich Sch Med & Dent, Windsor, ON N8X 2G1, Canada
关键词
Lansoprazole; Eosinophil Count; Distal Esophagus; Repeat Biopsy; Eosinophilic Esophagitis;
D O I
10.1186/1710-1492-7-10
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Eosinophilic gastroenteropathies, such as eosinophilic esophagitis and eosinophilic colitis, have classically been treated with swallowed inhaled corticosteroids or oral corticosteroids. More recent studies have found elimination and elemental diets to be effective treatment alternatives to steroids. In this case series we describe the treatment of three children using nutritional management in a community setting. Elimination diets and elemental diets based on patch testing and skin prick tests reduced the eosinophil counts to normal levels in all three children. Food items which tested positive were then reintroduced while symptoms and eosinophil counts were monitored. Nutritional management of eosinophilic esophagitis and eosinophilic colitis was found to be effective in reducing symptoms. However, obstacles facing patients who choose this type of therapy include limitations due to the cost of repeated endoscopies, palatability of elimination/elemental diets and the availability of subspecialists trained in management (e. g. Allergy, Gastroenterology, and Pathology). It may be a worthwhile endeavour to overcome these obstacles as nutritional management minimizes the potential long- term effects of chronic steroid therapy.
引用
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页数:4
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