Diagnostic, prognostic, and predictive biomarkers in pancreatic cancer

被引：197
作者：
Winter, Jordan M. [1 ]
Yeo, Charles J. [1 ]
Brody, Jonathan R. [1 ]
机构：
[1] Thomas Jefferson Univ, Dept Surg, Philadelphia, PA 19107 USA
来源：
JOURNAL OF SURGICAL ONCOLOGY | 2013年 / 107卷 / 01期
关键词：
pancreatic cancer; pancreatic ductal adenocarcinoma; biomarkers; predictive markers; prognostic markers; SERUM CA-19-9 LEVELS; GENE-EXPRESSION; ADJUVANT CHEMOTHERAPY; PHOSPHOGLYCERATE KINASE-1; DUCTAL ADENOCARCINOMA; CA19-9; LEVELS; SURVIVAL; GEMCITABINE; RECURRENCE; IDENTIFICATION;
D O I：
10.1002/jso.23192
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Serum CA 19-9 is the only FDA approved biomarker recommended for use in the routine management of pancreatic ductal adenocarcinoma (PDA). Over 2,000 biomarker studies related to pancreatic cancer appear in the literature, highlighting the need to discover and develop improved tests. Diagnostic biomarkers have implications for early detection of PDA, prognostic markers predict patient survival and recurrence patterns, and predictive markers can help personalize treatment regimens. J. Surg. Oncol. 2013;107:1522. (c) 2012 Wiley Periodicals, Inc.
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收藏
页码：15 / 22
页数：8
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