Common Sense Approach to Managing Sepsis

被引：4

作者：

Perner, Anders ^{[1
]}

Holst, Lars B. ^{[1
]}

Haase, Nicolai ^{[1
]}

Hjortrup, Peter B. ^{[1
]}

Moller, Morten H. ^{[1
]}

机构：

[1] Univ Copenhagen, Rigshosp, Dept Intens Care, Blegdamsvej 9, DK-2100 Copenhagen, Denmark

来源：

CRITICAL CARE CLINICS | 2018年 / 34卷 / 01期

关键词：

Sepsis; Resuscitation; Hemodynamic monitoring; Antibiotics; Critical care; Fluids; INTERNATIONAL CONSENSUS DEFINITIONS; PREDICTING FLUID RESPONSIVENESS; SEPTIC SHOCK; CARE; THERAPY; MANAGEMENT; OUTCOMES; TRIAL; RESUSCITATION; LEVOSIMENDAN;

D O I：

10.1016/j.ccc.2017.08.009

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Sepsis results in many deaths, prolonged suffering among survivors and relatives, and a high use of resources both in developed and developing countries. The updated Surviving Sepsis Campaign guidelines should aid clinicians in improving the identification and management of these patients, but many uncertainties remain because most of the guidance is based on low-quality evidence. This article discusses how to use some of the specific items of the guidelines together with a common-sense approach to aid clinical management of patients with sepsis while trying to balance the potential benefit and harm of the items.

引用

页码：127 / +

页数：13

共 61 条

[11]

Djogovic D, 2015, CAN J EMERG MED, V17, P1, DOI [10.1017/cem.2015.9, 10.1017/cem.2014.77]

[12] Intensive versus Conventional Glucose Control in Critically Ill Patients [J].

Finfer, S. ;

Blair, D. ;

Bellomo, R. ;

McArthur, C. ;

Mitchell, I. ;

Myburgh, J. ;

Norton, R. ;

Potter, J. ;

Chittock, D. ;

Dhingra, V. ;

Foster, D. ;

Cook, D. ;

Dodek, P. ;

Hebert, P. ;

Henderson, W. ;

Heyland, D. ;

McDonald, E. ;

Ronco, J. ;

Schweitzer, L. ;

Peto, R. ;

Sandercock, P. ;

Sprung, C. ;

Young, J. D. ;

Su, S. ;

Heritier, S. ;

Li, Q. ;

Bompoint, S. ;

Billot, L. ;

Crampton, L. ;

Darcy, F. ;

Jayne, K. ;

Kumarasinghe, V. ;

Little, L. ;

McEvoy, S. ;

MacMahon, S. ;

Pandey, S. ;

Ryan, S. ;

Shukla, R. ;

Vijayan, B. ;

Atherton, S. ;

Bell, J. ;

Hadfield, L. ;

Hourigan, C. ;

McArthur, C. ;

Newby, L. ;

Simmonds, C. ;

Buhr, H. ;

Eccleston, M. ;

McGuinness, S. ;

Parke, R. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (13) :1283-1297

[13] Protocols: help for improvement but beware of regression to the mean and mediocrity [J].

Girbes, Armand R. J. ;

Robert, Rene ;

Marik, Paul E. .

INTENSIVE CARE MEDICINE, 2015, 41 (12) :2218-2220

[14] Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis [J].

Gordon, A. C. ;

Perkins, G. D. ;

Singer, M. ;

McAuley, D. F. ;

Orme, R. M. L. ;

Santhakumaran, S. ;

Mason, A. J. ;

Cross, M. ;

Al-Beidh, F. ;

Best-Lane, J. ;

Brealey, D. ;

Nutt, C. L. ;

McNamee, J. J. ;

Reschreiter, H. ;

Breen, A. ;

Liu, K. D. ;

Ashby, D. .

NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (17) :1638-1648

[15] Hydroxyethyl starch 130/0.38-0.45 versus crystalloid or albumin in patients with sepsis: systematic review with meta-analysis and trial sequential analysis [J].

Haase, Nicolai ;

Perner, Anders ;

Inkeri, Louise ;

Siegemund, Martin ;

Lauridsen, Bo ;

Wetterslev, Mik ;

Wetterslev, Jorn .

BMJ-BRITISH MEDICAL JOURNAL, 2013, 346

[16] Thromboelastography in patients with severe sepsis: a prospective cohort study [J].

Haase, Nicolai ;

Ostrowski, Sisse Rye ;

Wetterslev, Jorn ;

Lange, Theis ;

Moller, Morten Hylander ;

Tousi, Hamid ;

Steensen, Morten ;

Pott, Frank ;

Soe-Jensen, Peter ;

Nielsen, Jonas ;

Hjortrup, Peter Buhl ;

Johansson, Par Ingemar ;

Perner, Anders .

INTENSIVE CARE MEDICINE, 2015, 41 (01) :77-85

[17] Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey [J].

Hemkens, Lars G. ;

Contopoulos-Ioannidis, Despina G. ;

Ioannidis, John P. A. .

BMJ-BRITISH MEDICAL JOURNAL, 2016, 352

[18] Effects of fluid restriction on measures of circulatory efficacy in adults with septic shock [J].

Hjortrup, P. B. ;

Haase, N. ;

Wetterslev, J. ;

Lange, T. ;

Bundgaard, H. ;

Rasmussen, B. S. ;

Dey, N. ;

Wilkman, E. ;

Christensen, L. ;

Lodahl, D. ;

Bestle, M. ;

Perner, A. .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 2017, 61 (04) :390-398

[19] Restricting volumes of resuscitation fluid in adults with septic shock after initial management: the CLASSIC randomised, parallel-group, multicentre feasibility trial [J].

Hjortrup, Peter B. ;

Haase, Nicolai ;

Bundgaard, Helle ;

Thomsen, Simon L. ;

Winding, Robert ;

Pettila, Ville ;

Aaen, Anne ;

Lodahl, David ;

Berthelsen, Rasmus E. ;

Christensen, Henrik ;

Madsen, Martin B. ;

Winkel, Per ;

Wetterslev, Jorn ;

Perner, Anders .

INTENSIVE CARE MEDICINE, 2016, 42 (11) :1695-1705

[20] Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis [J].

Holst, Lars B. ;

Petersen, Marie W. ;

Haase, Nicolai ;

Perner, Anders ;

Wetterslev, Jorn .

BMJ-BRITISH MEDICAL JOURNAL, 2015, 350

← 1 2 3 4 5 6 7 →