Rituximab for autoimmune blistering diseases: recent studies, new insights

被引:0
作者
Lunardon, L. [1 ]
Payne, A. S. [1 ]
机构
[1] Univ Penn, Dept Dermatol, Philadelphia, PA 19104 USA
来源
GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA | 2012年 / 147卷 / 03期
基金
美国国家卫生研究院;
关键词
Autoimmunity; Skin diseases; Pemphigus; EPIDERMOLYSIS-BULLOSA ACQUISITA; B-CELL DEPLETION; METHYLPREDNISOLONE PLUS AZATHIOPRINE; PEMPHIGUS-VULGARIS; MYCOPHENOLATE-MOFETIL; BONE-MARROW; CONSENSUS STATEMENT; ADJUVANT TREATMENT; ANTI-CD20; THERAPY;
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Rituximab, an anti-CD20 monoclonal antibody, has been successfully used off-label for treatment of autoimmune blistering diseases. We discuss rituximab mechanisms of action, host factors that may affect response to rituximab, and the efficacy and safety of rituximab in autoimmune blistering diseases, incorporating recent data on the use of rituximab in other autoimmune disease patients.
引用
收藏
页码:269 / 276
页数:8
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