A Wi-Fi Cloud-Based Portable Potentiostat for Electrochemical Biosensors

被引:34
作者
Bianchi, Valentina [1 ]
Boni, Andrea [1 ]
Fortunati, Simone [2 ]
Giannetto, Marco [2 ]
Careri, Maria [2 ]
De Munari, Ilaria [1 ]
机构
[1] Univ Parma, Dept Engn & Architecture, I-43124 Parma, Italy
[2] Univ Parma, Dept Chem Life Sci & Environm Sustainabil, I-43124 Parma, Italy
关键词
Analog front end; cloud services; Internet of Things (IoT); portable potentiostat; Wi-Fi; ACID;
D O I
10.1109/TIM.2019.2928533
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The measurement of the analyte concentration in electrochemical biosensors traditionally requires costly laboratory equipment to obtain accurate results. Innovative portable solutions have recently been proposed, but usually, they lean on personal computers (PCs) or smartphones for data elaboration and they exhibit poor resolution or portability and proprietary software. This paper presents a low-cost portable system, assembling an ad hoc-designed analog front end (AFE) and a development board equipped with a system on chip integrating a microcontroller and a Wi-Fi network processor. The wireless module enables the transmission of measurements directly to a cloud service for sharing device outcome with users (physicians, caregivers, and so on). In doing so, the system does not require neither the customized software nor other devices involved in data acquisition. Furthermore, when any Internet connection is lost, the data are stored on board for subsequent transmission when a Wi-Fi connection is available. The noise output voltage spectrum has been characterized. Since the designed device is intended to be battery-powered to enhance portability, investigations about battery lifetime were carried out. Finally, data acquired with a conventional benchtop Autolab PGSTAT-204 electrochemical workstation are compared with the outcome of our developed device to validate the effectiveness of our proposal. To this end, we selected ferri/ferrocyanide as redox probe, obtaining the calibration curves for both the platforms. The final outcomes are shown to be feasible, accurate, and repeatable.
引用
收藏
页码:3232 / 3240
页数:9
相关论文
共 24 条
[11]   A High-Efficiency Discrete Current Mode Output Stage Potentiostat Instrumentation for Self-Powered Electrochemical Devices [J].
Ghanbari, Sonia ;
Habibi, Mehdi ;
Magierowski, Sebastian .
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2018, 67 (09) :2247-2255
[12]   An integrated IoT-Wi-Fi board for remote data acquisition and sharing from innovative immunosensors. Case of study: Diagnosis of celiac disease [J].
Giannetto, Marco ;
Bianchi, Valentina ;
Gentili, Silvia ;
Fortunati, Simone ;
De Munari, Ilaria ;
Careri, Maria .
SENSORS AND ACTUATORS B-CHEMICAL, 2018, 273 :1395-1403
[13]   Amperometric Oxygen Sensor Based on a Platinum Nanoparticle-Modified Polycrystalline Boron Doped Diamond Disk Electrode [J].
Hutton, Laura ;
Newton, Mark. E. ;
Unwin, Patrick R. ;
Macpherson, Julie V. .
ANALYTICAL CHEMISTRY, 2009, 81 (03) :1023-1032
[14]   Wearable salivary uric acid mouthguard biosensor with integrated wireless electronics [J].
Kim, Jayoung ;
Imani, Somayeh ;
de Araujo, William R. ;
Warchall, Julian ;
Valdes-Ramirez, Gabriela ;
Paixao, Thiago R. L. C. ;
Mercier, Patrick P. ;
Wang, Joseph .
BIOSENSORS & BIOELECTRONICS, 2015, 74 :1061-1068
[15]   STEPPED-POTENTIAL VOLTAMMETRIES AT STATIONARY ELECTRODES .1. DIFFERENTIAL STAIRCASE, DIFFERENTIAL-PULSE AND SQUARE-WAVE VOLTAMMETRIES [J].
KRULIC, D ;
FATOUROS, N ;
ELBELAMACHI, MM .
JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1995, 385 (01) :33-38
[16]   Enzyme-Based Glucose Sensor: From Invasive to Wearable Device [J].
Lee, Hyunjae ;
Hong, Yongseok Joseph ;
Baik, Seungmin ;
Hyeon, Taeghwan ;
Kim, Dae-Hyeong .
ADVANCED HEALTHCARE MATERIALS, 2018, 7 (08)
[17]   Glucose biosensor based on open-source wireless microfluidic potentiostat [J].
Mercer, Conan ;
Bennett, Richard ;
Conghaile, Peter O. ;
Rusling, James F. ;
Leech, Donal .
SENSORS AND ACTUATORS B-CHEMICAL, 2019, 290 :616-624
[18]   Square-Wave Voltammetry: A Review on the Recent Progress [J].
Mirceski, Valentin ;
Gulaboski, Rubin ;
Lovric, Milivoj ;
Bogeski, Ivan ;
Kappl, Reinhard ;
Hoth, Markus .
ELECTROANALYSIS, 2013, 25 (11) :2411-2422
[19]  
Molderez T.R., IEEE T INSTRUM MEAS
[20]   Development of Optimized Screen-Printed Immunosensors [J].
Pernia, Alberto M. ;
Prieto, Miguel J. ;
Orille, Ivan C. ;
Martin-Ramos, Juan A. ;
Costa-Garcia, Agustin .
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2009, 58 (07) :2181-2188