Prenatal diagnosis of multicystic dysplastic kidney disease in the second trimester screening

被引：26

作者：

Al Naimi, Ammar ^{[1
]}

Baumueller, Jan-Eric ^{[1
]}

Spahn, Stephan ^{[1
]}

Bahlmann, Franz ^{[1
]}

机构：

[1] Burger Hosp, Dept Obstet & Gynecol, Frankfurt, Germany

来源：

PRENATAL DIAGNOSIS | 2013年 / 33卷 / 08期

关键词：

RENAL DYSPLASIA; ANOMALIES; CHILDREN; ULTRASOUND; MALFORMATIONS; FEATURES; AGENESIS; GROWTH; SIZE; RISK;

D O I：

10.1002/pd.4112

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Objective Multicystic dysplastic kidney (MCDK) is the most common antenatally diagnosed cystic renal pathology. It refers to the presence of multiple kidney cysts surrounded by dysplastic parenchymal tissue. Method We retrospectively review 54 cases (21 bilateral and 33 unilateral) with antenatally diagnosed MCDK between the years 1998 and 2012. We compare our data with the published literature and discuss different parameters. Results Our findings show a male predominance of 1.8:1 and a left side/right side ratio of 0.73:1. Most of the cases were isolated findings, but 20.3% were associated with anomalies. One case was a Goldenhar syndrome. Of the bilateral MCDK cases, 14.3% had chromosomal defects. Conclusion Isolated unilateral MCDK has good prognosis. Bad prognosis is linked to association with other anomalies as well as to bilateral MCDK. (c) 2013 John Wiley & Sons, Ltd.

引用

页码：726 / 731

页数：6

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