Monitoring neonatal seizures

被引:91
作者
Boylan, Geraldine B. [1 ]
Stevenson, Nathan J. [1 ]
Vanhatalo, Sampsa [2 ]
机构
[1] Natl Univ Ireland Univ Coll Cork, Neonatal Brain Res Grp, Dept Paediat & Child Hlth, Cork, Ireland
[2] Univ Helsinki, Cent Hosp, Hosp Children & Adolescents, Dept Clin Neurophysiol, Helsinki, Finland
基金
爱尔兰科学基金会; 英国惠康基金;
关键词
Electroencephalography (EEG); Monitoring; Multichannel EEG; Neonatal; Seizures; Automated detection; Algorithm; ELECTROGRAPHIC SEIZURES; NEWBORN EEG; ANTIEPILEPTIC DRUGS; PRETERM INFANTS; ELECTROENCEPHALOGRAPHY; MODEL; BURDEN; SYSTEM; CLASSIFICATION; ALGORITHM;
D O I
10.1016/j.siny.2013.04.004
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Neonatal seizures are a neurological emergency and prompt treatment is required. Seizure burden in neonates can be very high, status epilepticus a frequent occurrence, and the majority of seizures do not have any clinical correlate. Detection of neonatal seizures is only possible with continuous electroencephalogram (EEG) monitoring. EEG interpretation requires special expertise that is not available in most neonatal intensive care units (NICUs). As a result, a simplified method of EEG recording incorporating an easy:to-interpret compressed trend of the EEG output (amplitude integrated EEG) from one of the EEG output from one or two channels has emerged as a popular way to monitor neurological function in the NICU. This is not without limitations; short duration and low amplitude seizures can be missed, artefacts are problematic and may mimic seizure-like activity and only a restricted area of the brain is monitored. Continuous multichannel EEG is the gold standard for detecting seizures and monitoring response to therapy but expert interpretation of the EEG output is generally not available. Some centres have set up remote access for neurophysiologists to the cot-side EEG, but reliable interpretation is wholly dependent on the 24 h availability of experts, an expensive solution. A more practical solution for the NICU without such expertise is an automated seizure detection system. This review outlines the current state of the art regarding cot-side monitoring of neonatal seizures in the NICU. (C) 2013 Published by Elsevier Ltd.
引用
收藏
页码:202 / 208
页数:7
相关论文
共 75 条
  • [1] Automated neonatal seizure detection: A multistage classification system through feature selection basedon relevance and redundancy analysis
    Aarabi, A
    Wallois, F
    Grebe, R
    [J]. CLINICAL NEUROPHYSIOLOGY, 2006, 117 (02) : 328 - 340
  • [2] A multistage knowledge-based system for EEG seizure detection in newborn infants
    Aarabi, Ardalan
    Grebe, Reinhard
    Wallois, Fabrice
    [J]. CLINICAL NEUROPHYSIOLOGY, 2007, 118 (12) : 2781 - 2797
  • [3] Neonatal Seizures and Status Epilepticus
    Abend, Nicholas S.
    Wusthoff, Courtney J.
    [J]. JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2012, 29 (05) : 441 - 448
  • [4] Seizure detection in the neonatal EEG with synchronization likelihood
    Altenburg, J
    Vermeulen, RJ
    Strijers, RLM
    Fetter, WR
    Stam, CJ
    [J]. CLINICAL NEUROPHYSIOLOGY, 2003, 114 (01) : 50 - 55
  • [5] A new neurological focus in neonatal intensive care
    Bonifacio, Sonia L.
    Glass, Hannah C.
    Peloquin, Susan
    Ferriero, Donna M.
    [J]. NATURE REVIEWS NEUROLOGY, 2011, 7 (09) : 485 - 494
  • [6] Detection of subclinical electroencephalographic seizure patterns with multichannel amplitude-integrated EEG in full-term neonates
    Bourez-Swart, Mireille D.
    van Rooij, Linda
    Rizzo, Cristiano
    de Vries, Linda S.
    Toet, Mona C.
    Gebbink, Tineke A.
    Ezendam, Anja G. J.
    van Huffelen, Alexander C.
    [J]. CLINICAL NEUROPHYSIOLOGY, 2009, 120 (11) : 1916 - 1922
  • [7] Boylan GB, 2002, ARCH DIS CHILD-FETAL, V86, P165
  • [8] Electroencephalograms, clinical observations and the monitoring of neonatal seizures
    Bye, A
    Flanagan, D
    [J]. JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 1995, 31 (06) : 503 - 507
  • [9] A computer-aided detection of EEG seizures in infants: A singular-spectrum approach and performance comparison
    Celka, P
    Colditz, P
    [J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2002, 49 (05) : 455 - 462
  • [10] Nonlinear nonstationary Wiener model of infant EEG seizures
    Celka, P
    Colditz, P
    [J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2002, 49 (06) : 556 - 564