We introduce the notion of Killing normal Jacobi operator for real hypersurfaces in the complex quadric Q(m) = SOm+2/SOm+2/SO2 . The Killing normal Jacobi operator implies that the unit normal vector field N becomes U-principal or U-isotropic. Then according to each case, we give a complete classification of real hypersurfaces in Q(m) = SOm+2 / SOmSO2 with Killing normal Jacobi operator.