Calix[6]arene sulfonic acids catalysed Michael reactions of indoles with α,β-unsaturated ketones in water assisted by microwave radiation

被引：8

作者：

Xie, Yuanyuan ^{[1
]}

Mao, Linfeng ^{[1
]}

Li, Lehuan ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Key Lab Green Pharmaceut Technol & Related Equipm, Minist Educ, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2013年 / 08期

基金：

中国国家自然科学基金;

关键词：

Michael reactions; water-soluble calixarene; microwave irradiation; FRIEDEL-CRAFTS ALKYLATION; CONJUGATE ADDITION; IONIC LIQUID; DERIVATIVES;

D O I：

10.3184/174751913X13734725288804

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Michael reactions of indoles with alpha,beta-unsaturated ketones were carried out under microwave irradiation in water, affording the corresponding products in good to excellent yields. The calix[6] arene sulfonic acids bearing pendent aliphatic chains, as efficient surfactant-type acid catalysts, can be recovered after simple work-up and reused directly several times without loss of catalytic activity.

引用

页码：476 / 479

页数：4

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