QST-FST comparisons: evolutionary and ecological insights from genomic heterogeneity

被引：316

作者：

Leinonen, Tuomas ^{[1
]}

McCairns, R. J. Scott ^{[1
]}

O'Hara, Robert B. ^{[2
]}

Merila, Juha ^{[1
]}

机构：

[1] Univ Helsinki, Dept Biosci, Ecol Genet Res Unit, FI-00014 Helsinki, Finland

[2] Biodivers & Climate Res Ctr, D-60325 Frankfurt, Germany

来源：

NATURE REVIEWS GENETICS | 2013年 / 14卷 / 03期

基金：

芬兰科学院;

关键词：

QUANTITATIVE TRAIT LOCI; GENETIC DIFFERENTIATION; POPULATION-STRUCTURE; DIVERGENT SELECTION; NATURAL-SELECTION; F-ST; PHENOTYPIC PLASTICITY; STABILIZING SELECTION; ADAPTIVE DIVERGENCE; NEUTRAL MARKERS;

D O I：

10.1038/nrg3395

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Comparative studies of the divergence of quantitative traits and neutral molecular markers, known as Q(ST)-F-ST comparisons, provide a means for researchers to distinguish between natural selection and genetic drift as causes of population differentiation in complex polygenic traits. The use of Q(ST)-F-ST comparisons has increased rapidly in the last few years, highlighting the utility of this approach for addressing a wide range of questions that are relevant to evolutionary and ecological genetics. These studies have also provided lessons for the design of future Q(ST)-F-ST comparisons. Methods based on the Q(ST)-F-ST approach could also be used to analyse various types of 'omics' data in new and revealing ways.

引用

页码：179 / 190

页数：12

共 122 条

[21] A Genome-Scan Method to Identify Selected Loci Appropriate for Both Dominant and Codominant Markers: A Bayesian Perspective [J].

Foll, Matthieu ;

Gaggiotti, Oscar .

GENETICS, 2008, 180 (02) :977-993

[22] Speciation with gene flow in the large white-headed gulls: does selection counterbalance introgression? [J].

Gay, L. ;

Neubauer, G. ;

Zagalska-Neubauer, M. ;

Pons, J-M ;

Bell, D. A. ;

Crochet, P-A .

HEREDITY, 2009, 102 (02) :133-146

[23] The effects of dominance, regular inbreeding and sampling design on QST, an estimator of population differentiation for quantitative traits [J].

Goudet, J ;

Büchi, L .

GENETICS, 2006, 172 (02) :1337-1347

[24] Under neutrality, QST≤FST when there is dominance in an island model [J].

Goudet, Jerome ;

Martin, Gullaume .

GENETICS, 2007, 176 (02) :1371-1374

[25] Population differentiation and genetic variation inform translocation decisions for Liatris scariosa var. novae-angliae, a rare New England grassland perennial [J].

Gravuer, K ;

von Wettberg, E ;

Schmitt, J .

BIOLOGICAL CONSERVATION, 2005, 124 (02) :155-167

[26] Spontaneous Mutation Accumulation Studies in Evolutionary Genetics [J].

Halligan, Daniel L. ;

Keightley, Peter D. .

ANNUAL REVIEW OF ECOLOGY EVOLUTION AND SYSTEMATICS, 2009, 40 :151-172

[27] Application of SNPs for population genetics of nonmodel organisms: new opportunities and challenges [J].

Helyar, S. J. ;

Hemmer-Hansen, J. ;

Bekkevold, D. ;

Taylor, M. I. ;

Ogden, R. ;

Limborg, M. T. ;

Cariani, A. ;

Maes, G. E. ;

Diopere, E. ;

Carvalho, G. R. ;

Nielsen, E. E. .

MOLECULAR ECOLOGY RESOURCES, 2011, 11 :123-136

[28] QST>=≠<FST? [J].

Hendry, AP .

TRENDS IN ECOLOGY & EVOLUTION, 2002, 17 (11) :502-502

[29] What Animal Breeding Has Taught Us about Evolution [J].

Hill, William G. ;

Kirkpatrick, Mark .

ANNUAL REVIEW OF ECOLOGY, EVOLUTION, AND SYSTEMATICS, VOL 41, 2010, 41 :1-19

[30] Cryptic Variation in the Human Mutation Rate [J].

Hodgkinson, Alan ;

Ladoukakis, Emmanuel ;

Eyre-Walker, Adam .

PLOS BIOLOGY, 2009, 7 (02) :226-232

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