QST-FST comparisons: evolutionary and ecological insights from genomic heterogeneity

被引:314
作者
Leinonen, Tuomas [1 ]
McCairns, R. J. Scott [1 ]
O'Hara, Robert B. [2 ]
Merila, Juha [1 ]
机构
[1] Univ Helsinki, Dept Biosci, Ecol Genet Res Unit, FI-00014 Helsinki, Finland
[2] Biodivers & Climate Res Ctr, D-60325 Frankfurt, Germany
基金
芬兰科学院;
关键词
QUANTITATIVE TRAIT LOCI; GENETIC DIFFERENTIATION; POPULATION-STRUCTURE; DIVERGENT SELECTION; NATURAL-SELECTION; F-ST; PHENOTYPIC PLASTICITY; STABILIZING SELECTION; ADAPTIVE DIVERGENCE; NEUTRAL MARKERS;
D O I
10.1038/nrg3395
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Comparative studies of the divergence of quantitative traits and neutral molecular markers, known as Q(ST)-F-ST comparisons, provide a means for researchers to distinguish between natural selection and genetic drift as causes of population differentiation in complex polygenic traits. The use of Q(ST)-F-ST comparisons has increased rapidly in the last few years, highlighting the utility of this approach for addressing a wide range of questions that are relevant to evolutionary and ecological genetics. These studies have also provided lessons for the design of future Q(ST)-F-ST comparisons. Methods based on the Q(ST)-F-ST approach could also be used to analyse various types of 'omics' data in new and revealing ways.
引用
收藏
页码:179 / 190
页数:12
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