Curcumin and its derivatives prevent hepatocyte lipid peroxidation in Anabas testudineus

被引:6
|
作者
Manju, M. [1 ]
Sherin, T. G. [2 ]
Rajeesha, K. N. [2 ]
Sreejith, P. [1 ]
Rajasekharan, K. N. [2 ]
Oommen, O. V. [1 ]
机构
[1] Univ Kerala, Dept Zool, Thiruvananthapuram 695581, Kerala, India
[2] Univ Kerala, Dept Chem, Thiruvananthapuram 695581, Kerala, India
关键词
Anabas testudineus; antioxidants; curcuminoids; lipid peroxidation; liver;
D O I
10.1111/j.1095-8649.2008.02044.x
中图分类号
S9 [水产、渔业];
学科分类号
0908 ;
摘要
The present study evaluated the effect of five different curcuminoids, CURI, CURII, CURIII, a mixture of the three and a synthetic, curcumin-boron-oxalic acid complex, on Anabas testudineus hepatocyte lipid peroxidation after 30-60 min of incubation. The results showed that curcumin had a protective role as a strong antioxidant in teleosts. All the curcuminoids decreased the peroxidation products formed, with or without stimulating the antioxidant enzyme pathway. This suggests a direct reactive oxygen-species scavenging ability of curcuminoids. Their antioxidant effects appear to be time and dose-dependent.
引用
收藏
页码:1701 / 1713
页数:13
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