Short Sleep Duration and Erectile Dysfunction: A Review of the Literature

被引:17
作者
Zhang, Fuxun [1 ,2 ]
Xiong, Yang [1 ,2 ]
Qin, Feng [1 ]
Yuan, Jiuhong [1 ,2 ]
机构
[1] Sichuan Univ, West China Hosp, Androl Lab, Chengdu, Peoples R China
[2] Sichuan Univ, West China Hosp, Inst Urol, Dept Urol, Chengdu, Peoples R China
关键词
erectile dysfunction; molecular mechanisms; sleep disorder; short sleep duration; signaling pathway; AUTONOMIC NERVOUS-SYSTEM; NEUROPEPTIDE-Y; PENILE ERECTION; SHIFT WORK; SILDENAFIL CITRATE; SEXUAL DYSFUNCTION; CORTISOL SECRETION; SALIVARY CORTISOL; GENETIC-VARIATION; NEURAL-CONTROL;
D O I
10.2147/NSS.S375571
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The meaning of sleep has puzzled people for millennia. In modern society, short sleep duration is becoming a global problem. It has been established that short sleep duration can increase the risk of several diseases, such as cardiovascular and metabolic diseases. Currently, a growing body of research has revealed a possible link between sleep disorders and erectile dysfunction (ED). However, the mechanisms linking short sleep duration and ED are largely unknown. Thus, we provide a review of clinical trials and animal studies. In this review, we propose putative pathways connecting short sleep duration and ED, including neuroendocrine pathways and molecular mechanisms, aiming to pave the way for future research. Meanwhile, the assessment and improvement of sleep quality should be recommended in the diagnosis and treatment of ED patients.
引用
收藏
页码:1945 / 1961
页数:17
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