The Unstoppable Attraction for Induced Pluripotent Stem Cells Are They the Magic Bullet for Modeling Inherited Arrhythmogenic Diseases?

被引:5
作者
Gnecchi, Massimiliano [2 ]
Schwartz, Peter J. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Univ Pavia, Dept Mol Med, Fdn IRCCS Policlin S Matteo, I-27100 Pavia, Italy
[2] Fdn IRCCS Policlin S Matteo, Lab Expt Cardiol CCU, Pavia, Italy
[3] Univ Cape Town, Dept Med, Cardiovasc Genet Lab, Hatter Inst Cardiovasc Res Africa, ZA-7925 Cape Town, South Africa
[4] Univ Stellenbosch, Dept Med, ZA-7505 Tygerberg, South Africa
[5] King Saud Univ, Coll Med, Dept Family & Community Med, Riyadh 11461, Saudi Arabia
关键词
cardiomyocytes; catecholaminergic polymorphic ventricular tachycardia; human-induced pluripotent stem cells; inherited arrhythmogenic diseases; long QT syndrome; LONG-QT SYNDROME; MUTATIONS; SCN5A;
D O I
10.1016/j.jacc.2012.04.019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1001 / 1004
页数:4
相关论文
共 50 条
  • [31] The Application of Induced Pluripotent Stem Cells in Cardiac Disease Modeling and Drug Testing
    Ye, Lingqun
    Ni, Xuan
    Zhao, Zhen-Ao
    Lei, Wei
    Hu, Shijun
    JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 2018, 11 (05) : 366 - 374
  • [32] Modeling Neurodevelopmental and Neuropsychiatric Diseases with Astrocytes Derived from Human-Induced Pluripotent Stem Cells
    Ren, Baiyan
    Dunaevsky, Anna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (04) : 1 - 16
  • [33] Modeling Brain Disorders Using Induced Pluripotent Stem Cells
    Vadodaria, Krishna C.
    Jones, Jeffrey R.
    Linker, Sara
    Gage, Fred H.
    COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2020, 12 (06): : 1 - 15
  • [34] Modeling Choroideremia Disease with Isogenic Induced Pluripotent Stem Cells
    Fonseca, Ana Fragoso
    Coelho, Rita
    Lopes-da-Silva, Mafalda
    Lemos, Luisa
    Hall, Michael J.
    Oliveira, Daniela
    Falcao, Ana Sofia
    Tenreiro, Sandra
    Seabra, Miguel C.
    Antas, Pedro
    STEM CELLS AND DEVELOPMENT, 2024, 33 (19-20) : 528 - 539
  • [35] The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases
    Pourrier, Marc
    Fedida, David
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (02)
  • [36] Pluripotent Stem Cells and Human Diseases
    Zhang Wei-Qi
    Liu Guang-Hui
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2011, 38 (11) : 982 - 987
  • [37] Induced pluripotent stem cells in the inherited cardiomyopathies: From disease mechanisms to novel therapies
    Ross, Samantha Barratt
    Fraser, Stuart T.
    Semsarian, Christopher
    TRENDS IN CARDIOVASCULAR MEDICINE, 2016, 26 (08) : 663 - 672
  • [38] Induced pluripotent stem cells as cardiac arrhythmic in vitro models and the impact for drug discovery
    Saric, Tomo
    Halbach, Marcel
    Khalil, Markus
    Er, Fikret
    EXPERT OPINION ON DRUG DISCOVERY, 2014, 9 (01) : 55 - 76
  • [39] The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells
    Yokoo, Noritaka
    Baba, Shiro
    Kaichi, Shinji
    Niwa, Akira
    Mima, Takahiro
    Doi, Hiraku
    Yamanaka, Shinya
    Nakahata, Tatsutoshi
    Heike, Toshio
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 387 (03) : 482 - 488
  • [40] Human induced pluripotent stem cells for studying mitochondrial diseases in the heart
    Caudal, Arianne
    Ren, Lu
    Tu, Chengyi
    Wu, Joseph C.
    FEBS LETTERS, 2022, 596 (14) : 1735 - 1745