Controversies and advances in adrenal venous sampling in the diagnostic workup of primary aldosteronism

被引:29
作者
Wolley, Martin [1 ]
Thuzar, Moe [2 ,3 ]
Stowasser, Michael [1 ]
机构
[1] Univ Queensland, Princess Alexandra Hosp, Endocrine Hypertens Res Ctr, Diamantina Inst, 199 Ipswich Rd, Brisbane, Qld 4102, Australia
[2] Univ Queensland, Endocrine Hypertens Res Ctr, Diamantina Inst, 199 Ipswich Rd, Brisbane, Qld 4102, Australia
[3] Princess Alexandra Hosp, Dept Endocrinol, 199 Ipswich Rd, Brisbane, Qld 4102, Australia
关键词
primary aldosteronism; adrenal vein sampling; aldosterone producing adenoma; steroid profiling; ARM COMPUTED-TOMOGRAPHY; RAPID CORTISOL ASSAYS; SUPPRESSION; CONSENSUS; OUTCOMES; QUICK; CANNULATION; PREVALENCE; CRITERIA; CENTERS;
D O I
10.1016/j.beem.2020.101400
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Adrenal venous sampling (AVS) is a key part of the diagnostic workup of primary aldosteronism, distinguishing unilateral from bilateral disease and determining treatment options. Although AVS is a well-established procedure, many aspects remain controversial, including optimal patient selection for the procedure and exactly how AVS is performed and interpreted. Despite the controversies, a growing body of evidence supports the use of AVS in most patients with primary aldosteronism, though some specific patient groups may be able to forego AVS and proceed directly to treatment. Although AVS remains a difficult procedure, success rates may be improved with the use of advanced CT imaging techniques and/or rapid cortisol assays. New advances in nuclear imaging and steroid profiling may also offer alternatives or adjuncts to AVS in the future. (C) 2020 Published by Elsevier Ltd.
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页数:9
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