Advances in anion transport and supramolecular medicinal chemistry

被引：172
作者：
Davis, Jeffery T. [1 ]
Gale, Philip A. [2 ]
Quesada, Roberto [3 ]
机构：
[1] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA
[2] Univ Sydney, Sch Chem F11, Sydney, NSW 2006, Australia
[3] Univ Burgos, Dept Quim, Burgas 09001, Bulgaria
来源：
CHEMICAL SOCIETY REVIEWS | 2020年 / 49卷 / 16期
基金：
澳大利亚研究理事会;
关键词：
CHLORIDE TRANSPORT; ION CHANNELS; CYSTIC-FIBROSIS; CELL-DEATH; RECOGNITION; SQUARAMIDES; BINDING; DYSFUNCTION; RECEPTORS; APOPTOSIS;
D O I：
10.1039/c9cs00662a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Advances in anion transport by synthetic supramolecular systems are discussed in this article. Developments in the design of discrete molecular carriers for anions and supramolecular anion channels are reviewed followed by an overview of the use of these systems in biological systems as putative treatments for diseases such as cystic fibrosis and cancer.
引用
收藏
页码：6056 / 6086
页数：31
相关论文
共 111 条
  • [1] Tuning the solubility of ionophores: glutathione-mediated transport of chloride ions across hydrophobic membranes
    Akhtar, Nasim
    Pradhan, Nirmalya
    Saha, Abhishek
    Kumar, Vishnu
    Biswas, Oindrila
    Dey, Subhasis
    Shah, Manisha
    Kumar, Sachin
    Manna, Debasis
    [J]. CHEMICAL COMMUNICATIONS, 2019, 55 (58) : 8482 - 8485
  • [2] Diphenylethylenediamine-Based Potent Anionophores: Transmembrane Chloride Ion Transport and Apoptosis Inducing Activities
    Akhtar, Nasim
    Saha, Abhishek
    Kumar, Vishnu
    Pradhan, Nirmalya
    Panda, Subhankar
    Morla, Sudhir
    Kumar, Sachin
    Manna, Debasis
    [J]. ACS APPLIED MATERIALS & INTERFACES, 2018, 10 (40) : 33803 - 33813
  • [3] [Anonymous], 2000, Ion channels and disease
  • [4] 1,8-Diamidocarbazoles: an easily tuneable family of fluorescent anion sensors and transporters
    Bak, Krzysztof M.
    Chabuda, Krzysztof
    Montes, Helena
    Quesada, Roberto
    Chmielewski, Michal J.
    [J]. ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 16 (28) : 5188 - 5196
  • [5] Fluorescent squaramides as anion receptors and transmembrane anion transporters
    Bao, Xiaoping
    Wu, Xin
    Berry, Stuart N.
    Howe, Ethan N. W.
    Chang, Young-Tae
    Gale, Philip A.
    [J]. CHEMICAL COMMUNICATIONS, 2018, 54 (11) : 1363 - 1366
  • [6] Anion-Selective Cholesterol Decorated Macrocyclic Transmembrane Ion Carriers
    Behera, Harekrushna
    Madhavan, Nandita
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017, 139 (37) : 12919 - 12922
  • [7] Iodide-Selective Synthetic Ion Channels Based on Shape-Persistent Organic Cages
    Benke, Bahiru Punja
    Aich, Pulakesh
    Kim, Younghoon
    Kim, Kyung Lock
    Rohman, Md Rumum
    Hong, Soonsang
    Hwang, In-Chul
    Lee, Eun Hui
    Roh, Joon Ho
    Kim, Kimoon
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017, 139 (22) : 7432 - 7435
  • [8] Anion Transport with Chalcogen Bonds
    Benz, Sebastian
    Macchione, Mariano
    Verolet, Quentin
    Mareda, Jiri
    Sakai, Naomi
    Matile, Stefan
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (29) : 9093 - 9096
  • [9] Self-Assembly of Fluorinated Sugar Amino Acid Derived α,γ-Cyclic Peptides into Transmembrane Anion Transport
    Burade, Sachin S.
    Saha, Tanmoy
    Bhuma, Naresh
    Kumbhar, Navanath
    Kotmale, Amol
    Rajamohanan, Pattuparambil R.
    Gonnade, Rajesh G.
    Talukdar, Pinaki
    Dhavale, Dilip D.
    [J]. ORGANIC LETTERS, 2017, 19 (21) : 5948 - 5951
  • [10] Acyclic αγα-Tripeptides with Fluorinated- and Nonfluorinated-Furanoid Sugar Framework: Importance of Fluoro Substituent in Reverse-Turn Induced Self-Assembly and Transmembrane Ion-Transport Activity
    Burade, Sachin S.
    Shinde, Sopan Valiba
    Bhuma, Naresh
    Kumbhar, Navanath
    Kotmale, Amol
    Rajamohanan, Pattuparambil R.
    Gonnade, Rajesh G.
    Talukdar, Pinaki
    Dhavale, Dilip D.
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2017, 82 (11) : 5826 - 5834
12345678910