A multicenter randomized controlled trial for bright light therapy in adults with intellectual disabilities and depression: Study protocol and obstacle management

被引：8
作者：
Hamers, Pauline C. M. [1 ,2 ]
Evenhuis, Heleen M. [1 ]
Hermans, Heidi [1 ,2 ]
机构：
[1] Erasmus Univ, Med Ctr, Dept Gen Practice, Intellectual Disabil Med, POB 2040, NL-3000 CA Rotterdam, Netherlands
[2] Amarant Grp, Healthcare Org People Intellectual Disabil, Tilburg, Netherlands
来源：
RESEARCH IN DEVELOPMENTAL DISABILITIES | 2017年 / 60卷
关键词：
Bright light therapy; Depression; Intellectual disabilities; Randomized controlled trial; Circadian sleep-wake rhythm; Melatonin; Cortisol and stress; ABERRANT-BEHAVIOR-CHECKLIST; SEASONAL AFFECTIVE-DISORDER; NEGATIVE AIR IONS; OLDER-ADULTS; NONSEASONAL DEPRESSION; RHYTHM DISTURBANCES; SLEEP DISTURBANCES; CIRCADIAN-RHYTHMS; HAIR CORTISOL; DOUBLE-BLIND;
D O I：
10.1016/j.ridd.2016.10.012
中图分类号：
G76 [特殊教育];
学科分类号：
040109 ;
摘要：
Due to the limited cognitive and communicative abilities of adults with intellectual disabilities (ID), current treatment options for depression are often limited to lifestyle changes and pharmacological treatment. Bright light therapy (BLT) is an effective intervention for both seasonal and non-seasonal depression in the general population. BLT is an inexpensive, easy to carry out intervention with minimal side effects. However, knowledge on its anti-depressant effect in adults with ID is lacking. Obstacles in realizing a controlled intervention study in this particular study population may have contributed to this lack. To study the effect of BLT on depression in this population, it is necessary to successfully execute a multicenter randomized controlled trial (RCT). Therefore, the study protocol and the management of anticipated obstacles regarding this trial are presented. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：96 / 106
页数：11
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