Pulmonary function in patients surviving to COVID-19 pneumonia

被引：82

作者：

Fumagalli, Alessia ^{[1
]}

Misuraca, Clementina ^{[1
]}

Bianchi, Achille ^{[1
]}

Borsa, Noemi ^{[1
]}

Limonta, Simone ^{[2
]}

Maggiolini, Sveva ^{[1
]}

Bonardi, Daniela Rita ^{[1
]}

Corsonello, Andrea ^{[3
,4
]}

Di Rosa, Mirko ^{[3
,4
]}

Soraci, Luca ^{[3
,4
]}

Lattanzio, Fabrizia ^{[5
]}

Colombo, Daniele ^{[1
]}

机构：

[1] IRCCS INRCA Italian Natl Res Ctr Aging, Resp Unit, I-23880 Casatenovo, LC, Italy

[2] S Leopoldo Mand Hosp, Radiol Unit, I-23807 Merate, LC, Italy

[3] IRCCS INRCA Italian Natl Res Ctr Aging, Unit Geriatr Pharmacoepidemiol & Biostat, I-87100 Cosenza, CS, Italy

[4] IRCCS INRCA Italian Natl Res Ctr Aging, Unit Geriatr Med, I-87100 Cosenza, CS, Italy

[5] IRCCS INRCA Italian Natl Res Ctr Aging, Sci Direct, I-60124 Ancona, AN, Italy

来源：

INFECTION | 2021年 / 49卷 / 01期

关键词：

COVID-19; Pneumonia; Spirometry; SPIROMETRY; MORTALITY;

D O I：

10.1007/s15010-020-01474-9

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Purpose The aim of our study was to assess respiratory function at the time of clinical recovery and 6 weeks after discharge in patients surviving to COVID-19 pneumonia. Methods Our case series consisted of 13 patients with COVID-19 pneumonia. Results At the time of clinical recovery, FEV1 (2.07 +/- 0.72 L) and FVC (2.25 +/- 0.86 L) were lower compared to lower limit of normality (LLN) values (2.56 +/- 0.53 L,p= 0.004, and 3.31 +/- 0.65 L,p< 0.001, respectively), while FEV1/FVC (0.94 +/- 0.07) was higher compared to upper limit of normality (ULN) values (0.89 +/- 0.01,p= 0.029). After 6 weeks pulmonary function improved but FVC was still lower than ULN (2.87 +/- 0.81,p= 0.014). Conclusion These findings suggest that COVID-19 pneumonia may result in clinically relevant alterations in pulmonary function tests, with a mainly restrictive pattern.

引用

页码：153 / 157

页数：5

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