Advances in Anthrax Detection: Overview of Bioprobes and Biosensors

被引:24
作者
Kim, Joungmok [1 ]
Gedi, Vinayakumar [2 ,3 ]
Lee, Sang-Choon [2 ,3 ]
Cho, Jun-Haeng [2 ,3 ]
Moon, Ji-Young [2 ,3 ]
Yoon, Moon-Young [2 ,3 ]
机构
[1] Kyung Hee Univ, Sch Dent, Dept Oral Biochem & Mol Biol, Seoul 130701, South Korea
[2] Hanyang Univ, Dept Chem, Seoul 133791, South Korea
[3] Hanyang Univ, Inst Nat Sci, Seoul 133791, South Korea
基金
新加坡国家研究基金会;
关键词
Anthrax; Antibody; Aptamer; Bacillus anthracis; Detection; Peptide; Toxin; REAL-TIME PCR; LINKED-IMMUNOSORBENT-ASSAY; PEPTIDE NUCLEIC-ACIDS; BACILLUS-ANTHRACIS; PROTECTIVE ANTIGEN; CHROMOSOMAL MARKER; CUTANEOUS ANTHRAX; RAPID DETECTION; MOLECULAR CHARACTERIZATION; SENSITIVE DETECTION;
D O I
10.1007/s12010-015-1625-z
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Anthrax is an infectious disease caused by Bacillus anthracis. Although anthrax commonly affects domestic and wild animals, it causes a rare but lethal infection in humans. A variety of techniques have been introduced and evaluated to detect anthrax using cultures, polymerase chain reaction, and immunoassays to address the potential threat of anthrax being used as a bioweapon. The high-potential harm of anthrax in bioterrorism requires sensitive and specific detection systems that are rapid, field-ready, and real-time monitoring. Here, we provide a systematic overview of anthrax detection probes with their potential applications in various ultra-sensitive diagnostic systems.
引用
收藏
页码:957 / 977
页数:21
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