Syndecan-1 in the Tumor Microenvironment

被引:7
|
作者
Handra-Luca, Adriana [1 ,2 ]
机构
[1] Univ Sorbonne Paris Nord, Serv Anat Pathol, Bobigny, France
[2] Univ Sorbonne Paris Nord, APHP GHU Avicenne, Bobigny, France
关键词
Syndecan-1; Tumor; Stroma; Microenvironment; Pathology; Microscopy; Immunohistochemistry; Fibroblast; Vessels; Inflammatory cells; Extracellular matrix; Adenocarcinoma; Squamous cell carcinoma; Morphotype; Prognosis; STROMAL FIBROBLASTS; PROGNOSTIC VALUE; EXPRESSION; CELLS; CARCINOMAS; MYELOMA;
D O I
10.1007/978-3-030-48457-6_3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Syndecan-1 along with the other three syndecan proteins is present in the varied components of the tumor microenvironment: fibroblasts, inflammatory tumor immunity-associated cells, vessels, and extracellular matrix. Epithelial and non-epithelial tumors may show stromal syndecans. The main relevance of stromal syndecans as tumor biomarker resides in the relationships to tumor features such as type and differentiation as well as to prognosis.
引用
收藏
页码:39 / 53
页数:15
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