Is Flecainide Dangerous in Long QT-3 Patients?

被引:6
作者
Beinart, Roy
Michailidis, Athanasios
Gurevitz, Osnat T.
Glikson, Michael [1 ]
机构
[1] Chaim Sheba Med Ctr, Inst Heart, Pacing & Electrophysiol Unit, IL-52621 Tel Hashomer, Israel
来源
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY | 2009年 / 32卷 / 01期
关键词
long QT; defibrillation-ICD; BRUGADA-SYNDROME; MUTATION;
D O I
10.1111/j.1540-8159.2009.02190.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Mutations of the cardiac sodium channel gene, SCN5A, are present in both long-QT and Brugada syndromes. Flecainide is used as a provocative test to unmask the electrocardiogram (ECG) phenotype of the Brugada syndrome, as well as long-term treatment for long QT-3 syndrome, since it shortens the QT interval. We report a case where oral flecainide induced syncope with a Brugada ECG pattern in a patient with known long QT-3 syndrome. (PACE 2009; 32:143-145).
引用
收藏
页码:143 / 145
页数:3
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