Quantitative Fecal Lactoferrin in Toxin-Positive and Toxin-Negative Clostridium difficile Specimens

被引：24

作者：

LaSala, P. Rocco ^{[1
]}

Ekhmimi, Tariq

Hill, A. Kate

Farooqi, Imran

Perrotta, Peter L.

机构：

[1] W Virginia Univ, Dept Pathol, Robert C Byrd Hlth Sci Ctr, Morgantown, WV 26506 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2013年 / 51卷 / 01期

关键词：

GLUTAMATE-DEHYDROGENASE; LABORATORY DIAGNOSIS; STOOL SAMPLES; INFECTION; COLONIZATION; COLITIS; DISEASE; ASSAY; TCDB; PCR;

D O I：

10.1128/JCM.02735-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Quantitative fecal lactoferrin was measured in 112 patients tested for toxigenic Clostridium difficile using glutamate dehydrogenase (GDH) and toxin immunoassays combined with tcdB PCR. Lactoferrin levels were higher in the GDH-positive/toxin-positive group (79 mu g/ml) than in the GDH-positive/toxin-negative/PCR-positive (21 mu g/ml) and the GDH-negative groups (13 mu g/ml). Differences in fecal lactoferrin levels suggest variable presence or severity of C. difficile infection among toxin-positive and toxin-negative patients.

引用

页码：311 / 313

页数：3

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