Long-term intraspinal infusions of opioids with a new implantable medication pump

被引:0
作者
Likar, R
Spendel, MC
Amberger, W
Kepplinger, B
Supanz, S
Sadjak, A
机构
[1] Graz Univ, Inst Gen & Expt Pathol, A-8010 Graz, Austria
[2] Gen Hosp Klagenfurt, Dept Anaesthesiol & Intens Care, Amstetten, Austria
[3] Gen Hosp Klagenfurt, Dept Neurosurg, Amstetten, Austria
[4] Gen Hosp Klagenfurt, Dept Neurol, Amstetten, Austria
[5] Neurol Clin, Dept Neurol, Amstetten, Austria
来源
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH | 1999年 / 49卷 / 06期
关键词
implantable medication pump; pain relief; opioids; intrathecal; pain; chronic non-malignant; VIP; 30;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Experiences with long-term intraspinal infusion of opioid drugs using the new implantable medication pump VIP 30 in patients with chronic non-malignant pain are reported. During a 19-month period 10 patients with chronic pain - mainly mixed nociceptive-neuropathic pain underwent implantation of the medication pump for long-term treatment. The mean followup period was 9.5 months. Pain relief was classified as very good in 22.2 %, good in 44.4 %, moderate in 22.2 % and poor in 11.1 %. In 88.9 % of the cases the patients stated they would undergo the same procedure again. Technical problems (catheter dislocation) developed in 1/10 patients could be surgically corrected. One pump including catheter was explanted because of an infected seroma within the pocket area. Long-term intrathecal application of opioids with the VIP 30 pumps is an effective and safe treatment in patients with chronic non-malignant pain.
引用
收藏
页码:489 / 493
页数:5
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