Multidimensional LC separations in shotgun proteomics

被引:161
作者
Motoyama, Akira [1 ]
Yates, John R., III [2 ]
机构
[1] Shiseido Co, Yokohama, Kanagawa, Japan
[2] Scripps Res Inst, La Jolla, CA 92037 USA
关键词
D O I
10.1021/ac8013669
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Two modes of separation coupled with MS enable researchers to study complicated biological structures.
引用
收藏
页码:7187 / 7193
页数:7
相关论文
共 48 条
[11]   Review on the chemical and thermal stability of stationary phases for reversed-phase liquid chromatography [J].
Claessens, HA ;
van Straten, MA .
JOURNAL OF CHROMATOGRAPHY A, 2004, 1060 (1-2) :23-41
[12]  
Cole R.B., 1997, Electrospray Ionization Mass Spectrometry
[13]   Protein identification using sequential ion/ion reactions and tandem mass spectrometry [J].
Coon, JJ ;
Ueberheide, B ;
Syka, JEP ;
Dryhurst, DD ;
Ausio, J ;
Shabanowitz, J ;
Hunt, DF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (27) :9463-9468
[14]   Status of complete proteome analysis by mass spectrometry: SILAC labeled yeast as a model system [J].
de Godoy, Lyris M. F. ;
Olsen, Jesper V. ;
de Souza, Gustavo A. ;
Li, Guoqing ;
Mortensen, Peter ;
Mann, Matthias .
GENOME BIOLOGY, 2006, 7 (06)
[15]   Protein identification using 2D-LC-MS/MS [J].
Delahunty, C ;
Yates, JR .
METHODS, 2005, 35 (03) :248-255
[16]   Comprehensive multi-dimensional liquid chromatographic separation in biomedical and pharmaceutical analysis: a review [J].
Dixon, Steven P. ;
Pitfield, Ian D. ;
Perrett, David .
BIOMEDICAL CHROMATOGRAPHY, 2006, 20 (6-7) :508-529
[17]   Linear ion traps in mass spectrometry [J].
Douglas, DJ ;
Frank, AJ ;
Mao, DM .
MASS SPECTROMETRY REVIEWS, 2005, 24 (01) :1-29
[18]   AN APPROACH TO CORRELATE TANDEM MASS-SPECTRAL DATA OF PEPTIDES WITH AMINO-ACID-SEQUENCES IN A PROTEIN DATABASE [J].
ENG, JK ;
MCCORMACK, AL ;
YATES, JR .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1994, 5 (11) :976-989
[19]   Protein identification at the low femtomole level from silver-stained gels using a new fritless electrospray interface for liquid chromatography microspray and nanospray mass spectrometry [J].
Gatlin, CL ;
Kleemann, GR ;
Hays, LG ;
Link, AJ ;
Yates, JR .
ANALYTICAL BIOCHEMISTRY, 1998, 263 (01) :93-101
[20]   TWO-DIMENSIONAL SEPARATIONS - CONCEPT AND PROMISE [J].
GIDDINGS, JC .
ANALYTICAL CHEMISTRY, 1984, 56 (12) :1258-&