Synthesis of Mercaptobenzothiazole and Mercaptobenzimidazole Condensed with Inositol Derivatives

被引：4

作者：

de Assis, Joao Vitor ^{[1
]}

Couri, Mara Rubia C. ^{[1
]}

Porto, Ricardo Silva ^{[2
]}

de Almeida, Wagner B. ^{[3
]}

dos Santos, Leonardo H. R. ^{[1
]}

Diniz, Renata ^{[1
]}

de Almeida, Mauro V. ^{[1
]}

机构：

[1] Univ Fed Juiz de Fora, ICE, Dept Quim, BR-36036330 Juiz De Fora, MG, Brazil

[2] Univ Fed Alagoas, IQB, BR-57072970 Maceio, AL, Brazil

[3] Univ Fed Minas Gerais, ICEx, Dept Quim, BR-31270901 Belo Horizonte, MG, Brazil

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2013年 / 50卷

关键词：

STEREOSELECTIVE-SYNTHESIS; ANALOGS; QUEBRACHITOL; AGENTS; 1,4,5-TRISPHOSPHATE; PRECURSORS; SERIES;

D O I：

10.1002/jhet.1096

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This work describes the synthesis of inositol derivatives condensed with 2-mercaptobenzothiazole or 2-mercaptobenzimidazole, potential antimicrobial agents. These compounds were prepared by ring opening of epoxide intermediate (2S,3R-epoxy-1-O-methyl- l-chiro-inositol and 2R,3S-epoxy-1-O-methyl- l-chiro-inositol), which were obtained from l-quebrachitol (1-O-methyl-chiro-inositol). Microwave irradiation was used to promote the condensation reaction.

引用

页码：E142 / E147

页数：6

共 29 条

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