Antioxidant bisabolane-type sesquiterpenoids from algal-derived fungusAspergillus sydowiiEN-434

被引：15
|
作者：
Hu, Xueyi [1 ,2 ,3 ]
Li, Xiaoming [1 ,2 ,4 ]
Meng, Linghong [1 ,2 ,4 ]
Wang, Bingui [1 ,2 ,4 ]
机构：
[1] Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
[2] Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China
[3] Univ Chinese Acad Sci, Coll Earth Sci, Beijing 100049, Peoples R China
[4] Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China
来源：
JOURNAL OF OCEANOLOGY AND LIMNOLOGY | 2020年 / 38卷 / 05期
基金：
中国国家自然科学基金;
关键词：
Aspergillus sydowii; algal-derived fungus; bisabolene-type sesquiterpenoid; antioxidant activity; SYDONIC ACID; FUNGUS; METABOLITES;
D O I：
10.1007/s00343-020-0049-y
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
A new aromatic bisabolene-type sesquiterpenoid (7S-8S)-8-hydroxysydowic acid (1), together with a pair of new bisabolene derivative (+/-)-(7R*,10R*)-10-hydroxysydowic acid (2), as well as two known analogues hydroxysydonic acid (3) and sydowic acid (4) were isolated and identified from the endophytic fungal strainAspergillus sydowiiEN-434 that was obtained from the marine red algaSymphyocladia latiuscula. Their structures were elucidated by nuclear magnetic resonance (NMR), high resolution electrospray ionization mass spectroscopy (HRESIMS), and quantum chemical electronic circular dichroism (ECD) calculations as well as comparison of the data with literature reports. Compound1exhibited potent DPPH free radical scavenging activity with IC(50)value of 113.5 mu mol/L.
引用
收藏
页码：1532 / 1536
页数：5
相关论文
共 31 条
  • [21] Three New Sesquiterpenoids from the Algal-Derived Fungus Penicillium chermesinum EN-480
    Hu, Xue-Yi
    Li, Xiao-Ming
    Yang, Sui-Qun
    Liu, Hui
    Meng, Ling-Hong
    Wang, Bin-Gui
    MARINE DRUGS, 2020, 18 (04)
  • [22] Acetylcholinesterase Inhibitory Activity of Volatile Oil from Peltophorum dasyrachis Kurz ex Bakar (Yellow Batai) and Bisabolane-Type Sesquiterpenoids
    Fujiwara, Mai
    Yagi, Nobuo
    Miyazawa, Mitsuo
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (05) : 2824 - 2829
  • [23] Bisabolane sesquiterpene and cyclopentene derivatives from the marine algal-derived endophytic fungus Trichoderma asperellum EN-764
    Li, Hong-Lei
    Li, Xiao-Ming
    Ying, Zhen
    Li, Yan-He
    Wang, Bin-Gui
    PHYTOCHEMISTRY, 2023, 210
  • [24] Bisabolane-type sesquiterpenoids with potential anti-inflammatory and anti-HIV activities from the stems and leaves of Morinda citrifolia
    Zhao, Ying-Ying
    Li, Yu-Jie
    Yu, Xiao-Mei
    Su, Qin-Ting
    Wang, Li-Wen
    Zhu, Yu-Shu
    Fu, Yan-Hui
    Chen, Guang-Ying
    Liu, Yan-Ping
    NATURAL PRODUCT RESEARCH, 2023, 37 (12) : 1961 - 1968
  • [25] Comment on Acetylcholinesterase Inhibitory Activity of Volatile Oil from Peltophorum Dasyrachis Kurz Ex Bakar (Yellow Batai) and Bisabolane-Type Sesquiterpenoids
    Wiart, Christophe
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2013, 61 (28) : 7018 - 7018
  • [26] A strategy for identification and structural characterization of oplopane- and bisabolane-type sesquiterpenoids from Tussilago farfara L. by multiple scan modes of mass spectrometry
    Song, Kwangho
    Ha, In Jin
    Kim, Yeong Shik
    JOURNAL OF CHROMATOGRAPHY A, 2019, 1602 : 188 - 198
  • [27] Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501
    Li, Hong-Lei
    Li, Xiao-Ming
    Li, Xin
    Wang, Chen-Yin
    Liu, Hui
    Kassack, Matthias U.
    Meng, Ling-Hong
    Wang, Bin-Gui
    JOURNAL OF NATURAL PRODUCTS, 2017, 80 (01): : 162 - 168
  • [28] New quinoline alkaloid and bisabolane-type sesquiterpenoid derivatives from the deep-sea-derived fungus Aspergillus sp. SCSI006786
    Pang, Xiaoyan
    Lin, Xiuping
    Zhou, Xuefeng
    Yang, Bin
    Tian, Xinpeng
    Wang, Junfeng
    Xu, Shihai
    Liu, Yonghong
    FITOTERAPIA, 2020, 140
  • [29] Chermesins A-D: Meroterpenoids with a Drimane-Type Spirosesquiterpene Skeleton from the Marine Algal-Derived Endophytic Fungus Penicillium chermesinum EN-480
    Liu, Hui
    Li, Xiao-Ming
    Liu, Yang
    Zhang, Peng
    Wang, Jia-Ning
    Wang, Bin-Gui
    JOURNAL OF NATURAL PRODUCTS, 2016, 79 (04): : 806 - 811
  • [30] Bisabolane-type sesquiterpenoids from Curcuma longa L. exert anti-influenza and anti-inflammatory activities through NF-κB/MAPK and RIG-1/STAT1/2 signaling pathways
    Ti, Huihui
    Mai, Zhitong
    Wang, Zhoulang
    Zhang, Wenjie
    Xiao, Mengjie
    Yang, Zifeng
    Shaw, Pangchui
    FOOD & FUNCTION, 2021, 12 (15) : 6697 - 6711
1234