Influence of UV filters on the texture profile and efficacy of a cosmetic formulation

被引:12
|
作者
Fossa Shirata, M. M. [1 ]
Maia Campos, P. M. B. G. [1 ]
机构
[1] Univ Sao Paulo, Fac Pharmaceut Sci Ribeirao Preto, Ave Cafe,S-N Monte Alegre, BR-14040903 Ribeirao Preto, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
clinical efficacy; cosmetic formulations; skin barrier; texture; UV filters; IN-VITRO; SKIN; EMULSIONS; PROTECTION; ABSORBERS;
D O I
10.1111/ics.12424
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
ObjectiveConsidering that many cosmetic products contain UV filters in their composition and that few studies have evaluated the role of UV filters in the physical properties and clinical efficacy of these products, the aim of this study was to assess the influence of UV filters on the properties and immediate effects of a cosmetic formulation. MethodsFour cosmetic formulations, vehicle (V), vehicle containing UV filters (F), vehicle containing cassava polysaccharides and alfalfa (A) oligosaccharides and vehicle containing UV filters plus cassava polysaccharides and alfalfa oligosaccharides (multifunctional formulation, M) were developed. The texture profile of the formulations was analysed with a TA.XT plus Texturometer((R)). Twenty female volunteers aged 39-45 years were then selected for the assessment of immediate clinical efficacy of the formulations under study and of transepidermal water loss (TEWL), stratum corneum water content and microrelief of the skin obtained with their use. ResultsThe presence of UV filters resulted in an improvement of the physical properties of the multifunctional cosmetic formulation (M) and of skin microrelief. However, the presence of UV filters also caused a significant decrease in hydration. ConclusionThe presence of sunscreens had a negative influence on immediate skin hydration and TEWL. On the other hand, it positively influenced parameters related to the physical properties of the multifunctional formulation and skin microrelief. Thus, we conclude that the influence of UV filters on the development of cosmetic formulations is an important factor to be considered because it can have either positive or negative effect on the efficacy of the product.
引用
收藏
页码:622 / 628
页数:7
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