Metastatic Chromophobe Renal Cell Carcinoma in Pleural Fluid Cytology: Review of Literature and Report of a Case

被引：4

作者：

Davion, Simone ^{[1
]}

Rohan, Stephen ^{[1
]}

Nayar, Ritu ^{[1
]}

Kulesza, Peter ^{[1
]}

机构：

[1] Northwestern Univ, Chicago, IL 60606 USA

来源：

DIAGNOSTIC CYTOPATHOLOGY | 2012年 / 40卷 / 09期

关键词：

chromophobe; C-KIT; imatinib; KIT EXPRESSION; OVEREXPRESSION; ONCOCYTOMA; IMATINIB; FEATURES; THERAPY; CD117;

D O I：

10.1002/dc.21671

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The majority of chromophobe renal cell carcinomas (CHRCC) are not aggressive, however, a subset are. The potential for metastasis makes recognition of CHRCC cells in cytologic preparations important for patient surveillance, management, and treatment. We report the detection of an aggressive form of CHRCC in pleural fluid cytology with histopathologic confirmation on subsequent pleural biopsy. Sarcomatoid portions of the original CHRCC, and the pleural metastasis, demonstrated loss of diffuse membranous staining with C-KIT. Diagn. Cytopathol. 2012;40:826-829. (C) 2011 Wiley Periodicals, Inc.

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页码：826 / 829

页数：4

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