The effect of transcranial direct current stimulation on social cognition in schizophrenia: A preliminary study

被引：62

作者：

Rassovsky, Yuri ^{[1
,2
,3
]}

Dunn, Walter ^{[3
,4
]}

Wynn, Jonathan ^{[3
,4
]}

Wu, Allan D. ^{[5
]}

Iacoboni, Marco ^{[3
,6
]}

Hellemann, Gerhard ^{[3
]}

Green, Michael F. ^{[3
,4
]}

机构：

[1] Bar Ilan Univ, Dept Psychol, IL-52900 Ramat Gan, Israel

[2] Bar Ilan Univ, Gonda Multidisciplinary Brain Res Ctr, IL-52900 Ramat Gan, Israel

[3] UCLA Semel Inst Neurosci & Human Behav, Dept Psychiat & Biobehav Sci, Los Angeles, CA USA

[4] Dept Vet Affairs VISN 22 Mental Illness Res Educ, Los Angeles, CA USA

[5] Univ CA, Dept Neurol, Los Angeles, CA USA

[6] Univ CA, Ahmanson Lovelace Brain Mapping Ctr, Los Angeles, CA USA

来源：

SCHIZOPHRENIA RESEARCH | 2015年 / 165卷 / 2-3期

基金：

美国国家卫生研究院;

关键词：

Schizophrenia; Social cognition; Neurocognition; Transcranial direct current stimulation; tDCS; IMPROVE COGNITION; CLINICAL-TRIAL; TDCS; HALLUCINATIONS; BATTERY;

D O I：

10.1016/j.schres.2015.04.016

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

In this preliminary study, we examined the effect of transcranial direct current stimulation (tDCS) on social cognition in 36 individuals with schizophrenia. Participants received a baseline assessment and one week later received either anodal, cathodal, or sham tDCS, with 12 participants randomized to each condition. A single 20-minute session tDCS was administered bilaterally over the dorsolateral prefrontal cortex (centered at positions Fp1 and Fp2) at 2 mA. Among the 4 social cognitive tasks, participants showed a significant improvement on one of them, emotion identification, following anodal stimulation. Findings demonstrate the safety of this procedure and suggest potential therapeutic effects on one aspect of social cognition in schizophrenia. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：171 / 174

页数：4

共 34 条

[1] The neurobiology of social cognition [J].