Reduction of Phosphinites, Phosphinates, and Related Species with DIBAL-H

被引：12

作者：

Busacca, Carl A. ^{[1
]}

Bartholomeyzik, Teresa ^{[1
]}

Cheekoori, Sreedhar ^{[1
]}

Raju, Ravinder ^{[1
]}

Eriksson, Magnus ^{[1
]}

Kapadia, Suresh ^{[1
]}

Saha, Anian ^{[1
]}

Zeng, Xingzhong ^{[1
]}

Senanayake, Chris H. ^{[1
]}

机构：

[1] Boehringer Ingelheim Pharmaceut Inc, Dept Chem Dev, Ridgefield, CT 06877 USA

来源：

SYNLETT | 2009年 / 02期

关键词：

phosphorus; phosphines; phosphine boranes; reduction; BORANES; ACID; PHOSPHORUS; RESOLUTION; VERSATILE; ALKENES; OXIDES;

D O I：

10.1055/s-0028-1087671

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diisobutylaluminium hydride has been found to be an excellent reducing agent for phosphinites, phosphinates, and chlorophosphines. By performing reductions in situ, direct synthesis of secondary phosphine boranes from Grignard reagents has been achieved without isolation or purification of any intermediates.

引用

页码：287 / 291

页数：5

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