Intracellular membrane fusion: SNAREs only?

被引：77

作者：

Mayer, A ^{[1
]}

机构：

[1] Max Planck Gesell, Friedrich Miescher Lab, D-72076 Tubingen, Germany

来源：

CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 04期

关键词：

D O I：

10.1016/S0955-0674(99)80064-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The past two years have seen vigorous attempts to elucidate the mechanism driving intracellular membrane fusion, Much attention was focused on the role of SNARE complexes. Their crystal structure was solved and fusion was reconstituted using proteoliposomes with purified SNAREs suggesting them to be the minimal machinery for fusion. Work on physiological membranes, however, points in another direction and has spurred a hot debate on the function of SNAREs.

引用

页码：447 / 452

页数：6

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