Factors Predicting Ischemic-Type Biliary Lesions (ITBLs) After Liver Transplantation

被引：17

作者：

Frongillo, F. ^{[1
]}

Grossi, U. ^{[1
]}

Avolio, A. W. ^{[1
]}

Sganga, G. ^{[1
]}

Nure, E. ^{[1
]}

Pepe, G. ^{[1
]}

Bianco, G. ^{[1
]}

Lirosi, M. C. ^{[1
]}

Agnes, S. ^{[1
]}

机构：

[1] Univ Cattolica Sacro Cuore, Dept Gen Surg & Organ Transplantat, Policlin A Gemelli, I-00168 Rome, Italy

来源：

TRANSPLANTATION PROCEEDINGS | 2012年 / 44卷 / 07期

关键词：

RISK-FACTORS; COMPLICATIONS; STRICTURES;

D O I：

10.1016/j.transproceed.2012.06.008

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Among biliary complications, ischemic-type biliary lesions (ITBLs) remain a major cause of morbidity in liver transplant recipients, significantly affecting the chance of survival of both patients and grafts. We retrospectively reviewed 10 years of prospectively collected donor and recipient data from April 2001 to April 2011. We evaluated the incidence of ITBL occurrence, exploring the possible predisposing factors, including donor and recipient data. Two hundred fifty-one grafts were harvested: 222 of them were transplanted at our institution, the remaining 29 (11.6%) discarded by our donor team as showing >40% macrovesicular steatosis. Mild-moderate (20%-40%) macrovesicular steatosis (P < .001) and cold ischemia time (P = .048) significantly increased the risk of ITBL, also as an independent risk factor after multivariate analysis.

引用

页码：2002 / 2004

页数：3

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