Genetic and epigenetic perspective of microbiota

被引：8

作者：

Celiker, Cigdem ^{[1
]}

Kalkan, Rasime ^{[2
,3
]}

机构：

[1] Near East Univ, Arts & Sci Fac, Dept Mol Biol & Genet, CY-99138 Nicosia, Cyprus

[2] Near East Univ, Fac Med, Dept Med Genet, CY-99138 Nicosia, Cyprus

[3] Near East Univ, DESAM Inst, CY-99138 Nicosia, Cyprus

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2020年 / 104卷 / 19期

关键词：

Microbiota; Genetics; Epigenetics; CHAIN FATTY-ACIDS; GUT MICROBIOTA; COLORECTAL-CANCER; METHYLATION; MECHANISMS; DYSBIOSIS; METABOLISM; NUTRITION; OBESITY; FOLATE;

D O I：

10.1007/s00253-020-10849-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The gut microbiota has an extremely important role within the body and it is necessary for the regulation of the metabolism of the host and also for the development of metabolic diseases such as obesity. Here, we show several different factors leading to obesity such as epigenetic changes and how they result in differences to occur in the gut microbiota, along with gut dysbiosis which is caused by disturbances in the microbiota homeostasis. Several studies have been explained in this paper, providing evidence in how these findings can actually decrease the susceptibility of obesity, whether it be by changing an individual's diet pattern or observing the epigenetic changes which are taking place.

引用

页码：8221 / 8229

页数：9

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