Potentiometric Determination of Loperamide Hydrochloride by Loperamide PVC Membrane and Nano-Composite Electrodes

被引：0
|
作者：
Faridbod, F. [1 ,2 ]
Mizani, F. [3 ]
Ganjali, M. R. [1 ,2 ]
Norouzi, P. [1 ,2 ]
机构：
[1] Univ Tehran, Fac Chem, Ctr Excellence Electrochem, Tehran, Iran
[2] Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran
[3] Payame Noor Univ, Dept Chem, Tehran, Iran
来源：
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE | 2012年 / 7卷 / 08期
关键词：
Loperamide; Sensor; Potentiometry; Ion-selective electrode; PVC membrane; Carbon paste; Multi-walled carbon nanotubes; CARBON-PASTE ELECTRODE; ION-SELECTIVE ELECTRODE; NANOPOROUS SILICA-GEL; ANION RECOGNITION; SCHIFFS BASE; SENSOR;
D O I：
暂无
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
In this work, two new loperamide potentiometric electrodes were prepared and used for pharmaceutical analysis. In case of liquid membrane electrode, the best results were obtained from the electrode with the membrane composition of 5% ion-pair, 1% NaTPB, 30% PVC, and 64% DBP. The proposed sensor shows a Nernstian response (slope of 57.2 mV per decade) in the range of 3.0x10(-5)-1.0x10(-2) mol L-1. In case of carbon paste electrode modified by MWCNTs, calibration graph slope is about 58.5 mV per decade in the concentration range of loperamide hydrochloride 1.0x10(-5)-1.0x10(-2) mol L-1. Both sensors work well in the laboratory conditions and successfully applied in analysis of loperamide in some pharmaceutical formulations.
引用
收藏
页码：7643 / 7654
页数：12
相关论文
共 50 条
  • [41] PVC MATRIX MEMBRANE SENSORS FOR POTENTIOMETRIC DETERMINATION OF ARECOLINE
    Abounassif, A.
    Al-Hadiya, B. M.
    Mostafa, Gamal A. E.
    INSTRUMENTATION SCIENCE & TECHNOLOGY, 2010, 38 (02) : 165 - 177
  • [42] Potentiometric sensor for chromium(VI) using a composite of diphenylcarbazide-natural zeolite-modified membrane electrodes
    Heryanto, Rudi
    Rohaeti, Eti
    Wulansari, Laela
    Arif, Zulhan
    Wahyuni, Wulan Tri
    Putra, Budi Riza
    SCIENCEASIA, 2022, 48 (04): : 434 - 442
  • [43] A new nano-composite electrode as a copper (II) selective potentiometric sensor
    Afkhami, Abbas
    Khoshsafar, Hosein
    Madrakian, Tayyebeh
    Shirzadmehr, Ali
    JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2014, 11 (05) : 1373 - 1380
  • [44] PVC Membrane Potentiometric Sensor Based on a Schiff Base for Determination of Ho3+ ions
    Tamaddon, Atefeh
    Sadeghi, Hayedeh Bagheri
    Mollaei, Somayeh
    Ebrahimi, Arash Afshar
    ANALYTICAL & BIOANALYTICAL ELECTROCHEMISTRY, 2014, 6 (06): : 676 - 687
  • [45] A new nano-composite electrode as a copper (II) selective potentiometric sensor
    Abbas Afkhami
    Hosein Khoshsafar
    Tayyebeh Madrakian
    Ali Shirzadmehr
    Journal of the Iranian Chemical Society, 2014, 11 : 1373 - 1380
  • [46] Potentiometric PVC membrane ion–selective electrode for the determination of Sr(II) ions
    Özbek O.
    Sensors International, 2022, 3
  • [47] Development of PVC membrane potentiometric sensor for the determination of potassium ion and its applications
    Isildak, Omer
    Ozbek, Oguz
    Gurdere, Meliha Burcu
    Cetin, Alper
    PAMUKKALE UNIVERSITY JOURNAL OF ENGINEERING SCIENCES-PAMUKKALE UNIVERSITESI MUHENDISLIK BILIMLERI DERGISI, 2021, 27 (07): : 851 - 855
  • [48] PVC Membrane Sensors for Potentiometric Determination of Bambuterol in Pharmaceutical Formulation
    Ezzeldin, Essam
    Hefnawy, Mohammed M.
    Abounassif, Mohammed A.
    Tammam, Marwa H.
    Mostafa, Gamal A. E.
    INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2012, 7 (11): : 10570 - 10581
  • [49] Potentiometric Determination of Oxymetazoline Hydrochloride Using Modified Carbon Paste Electrodes
    Issa, Yousry M.
    Khalil, Mohamed M.
    Zayed, Sayed I. M.
    Mustafa, Naglaa
    PORTUGALIAE ELECTROCHIMICA ACTA, 2021, 39 (05) : 381 - 392
  • [50] Polymer membrane electrodes for sensitive potentiometric determination of β-blockers
    Wassil, Anwar A.
    Farag, Abd El-Ftaah Bastawy
    Moukdad, Fatma A.
    DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2007, 33 (01) : 57 - 62
12345