Regioselective base-induced condensations of acrylic acid derivatives

被引：8
作者：
Abdel-Ghani, E [1 ]
机构：
[1] Zagazig Univ, Fac Sci, Dept Chem, Zagazig, Egypt
来源：
JOURNAL OF CHEMICAL RESEARCH | 1999年 / 03期
关键词：
D O I：
10.1039/a803390k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The orientation of cyclization of the reaction of methyl aroylacrylate (1) and aroylacrylic acid (8) with ethyl acetoacetate and/or thiourea leading to the formation of 4-aroylmethylcyclopentane-1,3-dione (2) 5-aryl-3-oxocyclohexene-1,2-dicarboxylic acid (9), 2-imino-5-aroylmethylthiazolidin-4-one (11) and 6-aryl-2-sulfonylpyrimidine-4-carboxylic acid (14) depends on the medium employed; some compounds show moderate antiviral activities against tobacco necrosis virus.
引用
收藏
页码：174 / 175A
页数：5
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