Preexisting Right Ventricular Dysfunction Is Associated With Higher Postoperative Cardiac Complications and Longer Hospital Stay in High-Risk Patients Undergoing Nonemergent Major Vascular Surgery

被引:18
作者
Chou, Jody [1 ]
Ma, Michael [1 ]
Gylys, Maryte [1 ]
Seong, Jenny [1 ]
Salvatierra, Nicolas [1 ]
Kim, Robert [1 ]
Jiang, Luohua [2 ]
Barseghian, Ailin [3 ]
Rinehart, Joseph [1 ]
机构
[1] Univ Calif Irvine, Dept Anesthesiol & Perioperat Care, 333 City Blvd,West Suite 2150, Irvine, CA 92868 USA
[2] Univ Calif Irvine, Sch Med, Dept Epidemiol, Irvine, CA 92717 USA
[3] Univ Calif Irvine, Med Ctr, Internal Med, Dept Intervent Cardiol, Irvine, CA USA
关键词
right ventricular dysfunction; major vascular surgery; morbidity and mortality; EVENTS;
D O I
10.1053/j.jvca.2018.10.011
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Objectives: To evaluate whether the presence of preexisting right ventricular (RV) dysfunction in high-risk patients undergoing nonemergent major vascular surgery is associated independently with higher incidents of postoperative cardiac complications and a longer length of hospital stay. Design: Retrospective chart review. Setting: Single-center university hospital setting. Participants: The patient population consisted of those identified as American Society of Anesthesiologists classification III and above who had a preoperative echocardiogram within 1 year of undergoing nonemergent major vascular surgery between January 2010 and May 2017. Measurements and Main Results: After multivariate analyses, RV dysfunction (RVD) is associated independently with a higher incidence of postoperative major cardiac complications with an odds ratio = 6.3 (95% confidence interval [CI], 1.0-38.5; p = 0.046). In addition, patients with RVD had a 50% longer length of stay than those without RVD (incident rate ratio [95% CI], 1.5 [1.2-1.8]; p < 0.001). Conclusion: In this retrospective study of high-risk patients undergoing major vascular surgery, RV dysfunction was associated independently with a higher incidence of postoperative major cardiovascular events and longer length of hospital stays. Based on current findings, the prognostic value of RVD extends beyond the cardiac surgical cohort. Knowledge in management of patients with RVD in the perioperative setting should be understood by all anesthesiologists. Of note, a future study with a larger sample size is needed to validate the current findings given the small sample size of this study. Published by Elsevier Inc.
引用
收藏
页码:1279 / 1286
页数:8
相关论文
共 24 条
  • [1] [Anonymous], 2012, KIDNEY INT S
  • [2] Arko FR, 2002, J ENDOVASC THER, V9, P711, DOI 10.1583/1545-1550(2002)009<0711:ERREAL>2.0.CO
  • [3] 2
  • [4] Smeili LAA, 2015, ARQ BRAS CARDIOL, V105, P510
  • [5] The Vascular Study Group of New England Cardiac Risk Index (VSG-CRI) predicts cardiac complications more accurately than the Revised Cardiac Risk Index in vascular surgery patients
    Bertges, Daniel J.
    Goodney, Philip P.
    Zhao, Yuanyuan
    Schanzer, Andres
    Nolan, Brian W.
    Likosky, Donald S.
    Eldrup-Jorgensen, Jens
    Cronenwett, Jack L.
    [J]. JOURNAL OF VASCULAR SURGERY, 2010, 52 (03) : 674 - 683
  • [6] Pioglitazone and the secondary prevention of cardiovascular disease. A meta-analysis of randomized-controlled trials
    de Jong, Marit
    van der Worp, H. Bart
    van der Graaf, Yolanda
    Visseren, Frank L. J.
    Westerink, Jan
    [J]. CARDIOVASCULAR DIABETOLOGY, 2017, 16
  • [7] Perioperative Cardiac Damage in Vascular Surgery Patients
    Flu, W. -J.
    Schouten, O.
    van Kuijk, J. -P.
    Poldermans, D.
    [J]. EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 2010, 40 (01) : 1 - 8
  • [8] Galland RB, 1995, EUR J VASC ENDOVASC
  • [9] Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology
    Gorter, Thomas M.
    van Veldhuisen, Dirk J.
    Bauersachs, Johann
    Borlaug, Barry A.
    Celutkiene, Jelena
    Coats, Andrew J. S.
    Crespo-Leiro, Marisa G.
    Guazzi, Marco
    Harjola, Veli-Pekka
    Heymans, Stephane
    Hill, Loreena
    Lainscak, Mitja
    Lam, Carolyn S. P.
    Lund, Lars H.
    Lyon, Alexander R.
    Mebazaa, Alexandre
    Mueller, Christian
    Paulus, Walter J.
    Pieske, Burkert
    Piepoli, Massimo F.
    Ruschitzka, Frank
    Rutten, Frans H.
    Seferovic, Petar M.
    Solomon, Scott D.
    Shah, Sanjiv J.
    Triposkiadis, Filippos
    Wachter, Rolf
    Tschoepe, Carsten
    de Boer, Rudolf A.
    [J]. EUROPEAN JOURNAL OF HEART FAILURE, 2018, 20 (01) : 16 - 37
  • [10] Gut Microbiota Metabolites and Risk of Major Adverse Cardiovascular Disease Events and Death: A Systematic Review and Meta-Analysis of Prospective Studies
    Heianza, Yoriko
    Ma, Wenjie
    Manson, JoAnn E.
    Rexrode, Kathryn M.
    Qi, Lu
    [J]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2017, 6 (07):