Monoclonal cryo-antifibrinogenemia

被引：20

作者：

Euler, HH ^{[1
]}

Zeuner, RA ^{[1
]}

Beress, R ^{[1
]}

Gutschmidt, HJ ^{[1
]}

Christophers, E ^{[1
]}

Schroeder, JO ^{[1
]}

机构：

[1] MUNICIPAL HOSP,KIEL,GERMANY

来源：

ARTHRITIS AND RHEUMATISM | 1996年 / 39卷 / 06期

关键词：

D O I：

10.1002/art.1780390628

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report on a 54-year-old female patient with arthritis and a severe cold-induced leukocytoclastic vasculitis of the skin caused by a rare form of cryofibrinogenemia (''type II'' cryofibrinogen). Affinity chromatography of cryoprecipitates from the patient's plasma revealed reversible cryoprecipitability of complexes composed of fibrinogen and a monoclonal antifibrinogen antibody (IgG3 kappa). Conventional serum and plasma electrophoresis did not detect the paraprotein. Control of symptoms was achieved by long-term plasmapheresis.

引用

页码：1066 / 1069

页数：4

共 15 条

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