Postnatal testicular development in the Chinchilla rabbit

The Chinchilla rabbit is a breed with high commercial value and nowadays is increasingly used in various fields of biomedical research, however, its postnatal reproductive biology has been little studied. The aim of the present study was to investigate the postnatal development of the testis in this rabbit breed to determine both the proliferative periods and apoptosis. 30 rabbits aged 3-100 days old were used in the study. Determination of the period of differentiation of gonocytes to spermatogonia (50 dpp), the periods of proliferation and apoptosis of their cells, as well as the beginning of spermatogenesis (60 dpp) and the different stages of the seminiferous epithelium cycle were made. We found that these testicular developments were closer to that of humans when compared with rats, a species commonly employed in reproductive research. On comparing these results with those obtained from other breeds, there are clear differences favoring the use of this species as a research model in the field of male reproductive biology. (C) 2013 Elsevier GmbH. All rights reserved.