Primary large cell neuroendocrine carcinoma of the urinary bladder

被引：26

作者：

Akamatsu, Shusuke ^{[1
]}

Kanamaru, Sojun ^{[1
]}

Ishihara, Misa ^{[2
]}

Sano, Takeshi ^{[1
]}

Soeda, Asaki ^{[1
]}

Hashimoto, Kimio ^{[2
]}

机构：

[1] Nishi Kobe Med Ctr, Dept Urol, Kobe, Hyogo, Japan

[2] Nishi Kobe Med Ctr, Dept Pathol, Kobe, Hyogo, Japan

来源：

INTERNATIONAL JOURNAL OF UROLOGY | 2008年 / 15卷 / 12期

关键词：

carcinoma; large cell; neuroendocrine; small cell; urinary bladder;

D O I：

10.1111/j.1442-2042.2008.02168.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Large cell neuroendocrine carcinoma (LCNEC) of the urinary bladder is rare. It is a type of neuroendocrine carcinoma morphologically distinct from small cell carcinoma. We report here a case of primary LCNEC of the urinary bladder. We observed a very large invasive tumor, which was not able to be detected three months previously by cystoscopy or computed tomography. The tumor cells morphologically and immunohistochemically resembled that of pulmonary LCNEC. With prompt cystoprostatectomy and chemotherapy, the patient is free of disease 16 months after diagnosis. Although LCNEC is usually very aggressive, it may be controlled by early diagnosis and treatment.

引用

页码：1080 / 1083

页数：4

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